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不同麻醉方法对非体外循环冠脉搭桥患者术后早期认知功能的影响
引用本文:邹捍东,吴灵潝,周青山,程邦昌. 不同麻醉方法对非体外循环冠脉搭桥患者术后早期认知功能的影响[J]. 现代中西医结合杂志, 2010, 19(4): 391-392,410
作者姓名:邹捍东  吴灵潝  周青山  程邦昌
作者单位:武汉大学人民医院,湖北,武汉,430060
摘    要:目的观察丙泊酚和七氟烷对非体外循环下冠状动脉搭桥(OPCABG)患者术后早期认知功能的影响。方法选择60例择期行OPCABG术患者,随机分为丙泊酚组(P组)和七氟烷组(S组),每组30例,分别用丙泊酚或七氟烷麻醉,术中脑电双频指数(BIS)维持于40~55。观察患者术后苏醒情况,并记录术前及拔管后1 h、3 h、6 h、24 h的MMSE评分。结果2组患者术后苏醒时间、拔管时间、拔管后话语时间均无显著性差异;拔管后,2组患者1 h3、h的MMSE评分均低于术前(P均0.05),拔管后6 h MMSE评分恢复至术前水平。2组患者拔管后1 h、3 h、6 h、24 h的MMSE评分均无显著性差异。拔管后1 h,P组有6例(20%)、S组有8例(27%)患者的MMSE评分低于24分。结论全凭丙泊酚或七氟烷麻醉用于OPCABG患者安全有效,术后苏醒快,早期认知功能障碍持续时间短暂。

关 键 词:丙泊酚  七氟烷  冠状动脉分流术  认知功能

Effects of different anesthesia methods on early post-operative cognitive function in off-pump coronary arteria bypass graft surgery patients
Zou Handong,Wu Lingxi,Zhou Qingshan,Cheng Bangchang. Effects of different anesthesia methods on early post-operative cognitive function in off-pump coronary arteria bypass graft surgery patients[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2010, 19(4): 391-392,410
Authors:Zou Handong  Wu Lingxi  Zhou Qingshan  Cheng Bangchang
Affiliation:Zou H,ong,Wu Lingxi,Zhou Qingshan,Cheng Bangchang(The People's Hospital of Wuhan University,Wuhan 430060,Hubei,China)
Abstract:Objective It is to observe the effects of Propofol and sevoflurane on the early post-operative cognitive function in off-pump coronary artery bypass graft surgery patients.Methods Sixty patients undergoing off-pump coronary artery bypass graft surgery were randomly assigned to group P and group S.Each group had 30 cases.During operation,Propofol or sevoflurane were administered to maintain BIS values between 40 to 55.The time of awaking,the mini-mental state examination(MMSE)was recorded to assess the cogni...
Keywords:Propofol  sevoflurane  coronary artery bypass graft  cognitive function  
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