空腹血糖升高对急性心肌梗死后左室射血分数的影响

目的 观察空腹血糖水平升高对急性心肌梗死(AMI)后左室射血分数(LVEF)的影响.方法 入选首次AMI患者共161例,以入院后24h内空腹8h后测定的血糖水平为空腹血糖水平.根据空腹血糖水平分为三组:1组,空腹血糖＜6.1mmol/L;2组,空腹血糖6.1-6.9 mmool/L;3组空腹血糖≥7.0 mmol/L,空腹血糖水平升高包括2组与3组.所有患者分别于发病后72h内、发病后30d行超声心动图检查测量LYEF.结果 2组和3组入院时及30d随访时的LVEF明显低于1组[入院时:(49.3±6.7)%、(45.8±7.4)%比(52.4±7.7)%,P＜0.05;30 d随访时:(52.7±7.3)%、(49.2士7.2)%比(55.8±7.4)%,P＜0.05].结论 AMI后空腹血糖水平升高是常见的临床特点,合并空腹血糖水平升高的AMI患者的LYEF降低更为明显.

The influence of elevated fasting blood glucose on left ventricular ejection fraction after acute myocardial infarction

Objective To investigate the inttuenee of elevated fasting blood glucose(FBG)on left ventrieular ejection fraction(LVEF)after acute myocardial infarction(AMI).Methods The relationship between FBG(≥8-hour fast within 24 hours of admission)and LVEF in 161 patients with AMI was studied prospectively.Patients were grouped by FBG (group 1,FBG＜6.1 mmol/L,group 2,FBG 6.1-6.9mmol/L,group 3.FBG≥7.0mmol/L).LVEF was measured at admission and at 30 days after AMI onset Results Compared with that of normal FBG(group 1),LYEF of elevated FBG(group 2 and group 3)was lower[for admission:(49.3±6.7)%,(45.8±7.4)% vs (52.4±7.7)%,P＜0.05;for 30day8:(52.7±7.3)%,(49.2±7.2)% vs (55.8±7.4)%.P＜0.05].ConclusionElevated FBG is associated with worse LVEF after AMI.