| 复方奥硝唑含漱液的制备及质量控制 |
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| 引用本文： | 陈雅,杨征,吴畏,舒凌玲,党莉. 复方奥硝唑含漱液的制备及质量控制[J]. 中国药师, 2005, 8(1): 36-37 |
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| 作者姓名： | 陈雅 杨征 吴畏 舒凌玲 党莉 |
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| 作者单位： | 第三军医大学野战外科研究所大坪医院药学部,重庆,400042 |
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| 摘 要： | 目的:制备复方奥硝唑含漱液并建立其含量测定方法.方法:将奥哨唑和醋酸氯已定制成含漱剂,采用双波长分光光度法在317 nm波长处测定奥硝唑含量,在247 nm和278 nm波长处测定醋酸氯已定含量.结果:奥硝唑的平均回收率为99.66%,RSD=0.40%(n=5);醋酸氯已定的平均回收率为100.21%,RSD=0.84%(n=5).结论:该制剂制备方法简便易行,质量可控,适于医院使用.
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| 关 键 词： | 奥硝唑含漱液,复方 制备 分光光度法 |
| 文章编号： | 1008-049X(2005)01-0036-02 |
| 修稿时间： | 2003-12-22 |
Preparation and Quality Control of Compound Ornidazole Gargle |
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| Chen Y,Yang Zheng,Wu Wei,Shu Lingling,Dang Li. Preparation and Quality Control of Compound Ornidazole Gargle[J]. China Pharmacist, 2005, 8(1): 36-37 |
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| Authors: | Chen Y Yang Zheng Wu Wei Shu Lingling Dang Li |
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| Abstract: | Objective: To prepare the compound ornidazole gargle and determine its contents. Method: Dual wavelength spectro-photomrtry was used to determine ornidazole at 317 nm. The content of chlorhexidine acetate was determined at 247 nm and 278 nm. Result: The average recoveries of ornidazole and chlorhexidine acetate were 99.66% ( RSD =0.40% ) and 100.21% ( RSD = 0. 84% ) ,respectively. Conclusion: The preparing method is simple and the quality control is accurate. |
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| Keywords: | Ornidazole gargle compound Preparation Spectrophotomrtry dual wavelength |
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