首发精神分裂症病人的攻击行为与部分血脂水平的关系

目的 探讨血清胆固醇、甘油三脂、高密度脂蛋白水平与精神分裂症病人攻击行为的关系。方法 从既往史中有无攻击行为和采用外显攻击行为量表(MOAS)评分以区分有攻击行为者(研究组)和无攻击行为者(对照组)，并比较两组上述血脂的水平；同时采用BPRS量表评定精神症状以比较与血脂水平变化的关系。结果 研究组的胆固醇水平显著低于对照组，而高密度脂蛋白水平及BPRS量表的总分及激活性、敌对猜疑因子分显著高于对照组。结论 精神分裂症病人的攻击行为可能与胆固醇水平低、高密度脂蛋白水平高有关。

The relationship between serum lipid levels and impusive aggression in the first episode of patients with schizophrenia

Objective To investigate the relationship between serum cho-lesterol(CHO),triglyeride(TG),high density lipoprotein(HDL-C) levels and impulsive aggression of the first episode of patients with schizophrenia.Method According to impusive aggression in the past violence history and rating on the modified overt aggression scale(MOAS),80 the first onset of in-patients with schizophrenia were divided into research group and control group.Serum lipid levels and brief psychiatric rating scals(BPRS) were compared between two groups.Results There is significanly lower CHO level in research group than in control.The HDL-C level,the total score of BPRS and its factors scores including irriability,hoslility and harbour suspicion in reseach groups were higher than in controls.Conclusion It is indicated that impulsive aggression might relate to low CHO or high HDL-C level in patients with schizophrenia.