| 冠心病患者脂质过氧化反应与血液流变学变化的研究 |
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| 引用本文： | 李悦山,薛磊,祁桂英,王月香.冠心病患者脂质过氧化反应与血液流变学变化的研究[J].中国血液流变学杂志,1995(1). |
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| 作者姓名： | 李悦山 薛磊 祁桂英 王月香 |
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| 作者单位： | 石河子医学院病理生理教研室!(新疆832002(李悦山)，石河子八一棉纺织厂职工医院(薛磊)，石河子医学院附属医院心内科(祁桂英，王月香) |
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| 摘 要： | 测定了３０例冠心病（ＣＨＤ）患者和３０例正常人血浆丙二醛（ＭＤＡ）含量、红细胞超氧化物歧化酶（ＳＯＤ）、全血谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）活力和部分血液流变学指标。结果表明，ＣＨＤ心绞痛发作期机体抗氧化能力明显降低，自由基增多及血液粘度增大，提示自由基损伤及脂质过氧化和高血粘度。Ｓｖａｔｅ有抗脂质过氧化及降低血浆纤维蛋白原的作用。
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| 关 键 词： | 冠心病 血液流变学 |
STUDY ON CHANGES OF LIPID PEROXIDATION AND HEMORHEOLOGY IN CORONARY HEART DISEASE |
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| Li Yuc- Shan,et al.STUDY ON CHANGES OF LIPID PEROXIDATION AND HEMORHEOLOGY IN CORONARY HEART DISEASE[J].Chinese Journal of Hemorheology,1995(1). |
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| Authors: | Li Yuc- Shan |
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| Institution: | Li Yuc- Shan,et al Department of Pathophysiology,Shihezi Medical College Xinjing 832002 |
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| Abstract: | The plasma malondialdehyde (MDA)contents, erythrocyte superoxide dismutase (SOD) activities, blood glutathione peroxidase (GSH-Px) activities and some hemorheological parameters were determined in 30 patients with coronary he- art disease (CHD group)and 30 healthy individuals(control group). The above data indicatted that frce radical-mediated damage and.the increased lipid peroxidation may play an importent role in severe myocardialischemic damage of the patients with CHD. The lipid peroxidation may cause the blood hyperviscosity of the pat-ients with CHD. Svate possesed the effects of.antilipid peroxidation and red-ucing plasma fibrinogen content. |
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| Keywords: | hemorheology coronary heart disease |
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