Diagnostic performance of ultrasound in patients with suspected brachial plexus lesions in adults: a multicenter retrospective study with MRI, surgical findings and clinical follow-up as reference standard |
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Authors: | Alberto Tagliafico Giulia Succio Giovanni Serafini Carlo Martinoli |
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Affiliation: | 1. Department of Human Anatomy, DIMES, Università di Genova, Genoa, Italy, Largo Rosanna Benzi 8, 16138, Genova, Italy 2. Department of Radiology, Santa Corona Hospital, Pietra Ligure, Italy, via XXV Aprile, 38, Pietra Ligure, 17027, Savona, Italy 3. Radiology Department, DISC, Università di Genova, Genoa, Italy, Largo Rosanna Benzi 8, 16138, Genova, Italy
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Abstract: | Purpose To evaluate brachial plexus ultrasound (US) performance in a large multicenter study. Materials and methods The research was approved by the Institutional Review Boards, and all patients gave written informed consent. A multicenter retrospective trial including three centers was performed between March, 2006 and April, 2011. A total of 204 patients who received a brachial plexus ultrasound requested by the referring physician were enrolled: magnetic resonance imaging, surgical findings and clinical follow-up of at least 12 months were used as the reference standard. Sensitivity, specificity with 95 % confidence intervals (CIs), positive predictive value (PPV), pre-test-probability (the prevalence), negative predictive value (NPV), pre- and post- test odds (OR), likelihood ratio for positive results (LH+), likelihood ratio for negative results (LH-), accuracy and post-test probability (post-P) were reported on a per-patient basis. Results The overall sensitivity and specificity with 95 % CIs were: 0.76 (0.75–0.97); 0.96 (0.77–0.89). Overall PPV, pre-test probability, NPV, pre-OR, post-OR, LH+, LH-, Accuracy and post-P were: 0.93/0.43/0.84/0.75/0.75/13.4/17.6/0.25/0.88/0.93, respectively. Conclusions The specificity of brachial plexus US in patients suspected of having a brachial plexus lesion is very high. |
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