| 肾上腺糖皮质激素治疗成人全身型重症肌无力21例疗效观察 |
| |
| 引用本文： | 张可真,王言飞,闫丙川.肾上腺糖皮质激素治疗成人全身型重症肌无力21例疗效观察[J].中国实用神经疾病杂志,2006,9(6):44-45. |
| |
| 作者姓名： | 张可真 王言飞 闫丙川 |
| |
| 作者单位： | 河南漯河市中心医院神经内科,漯河,462000;河南漯河市中心医院神经内科,漯河,462000;河南漯河市中心医院神经内科,漯河,462000 |
| |
| 摘 要： | 目的 观察肾上腺糖皮质激素治疗成人全身型重症肌无力（MG）的疗效、疗程及不良反应。方法 对21例患者用大剂量激素递减法治疗。结果 激素治疗有效率100％，激素起效时间：胸腺异常组迟于胸腺正常组（P〈0．01）；严重全身型迟于轻度全身型（P〈0.01）。结论 对未能用抗胆碱酯酶药及胸腺切除术得到良好控制的MG患者，可首选肾上腺糖皮质激素。
|
| 关 键 词： | 重症肌无力 糖皮质激素 疗效 |
| 文章编号： | 1673-5110（2006）06-0044-02 |
| 收稿时间： | 2006-06-28 |
| 修稿时间： | 2006年6月28日 |
Observation of the efficacy of adreno-corticosteroid in 21 adult patients with generalized myasthenia gravis |
| |
| Zhang Kezhen,Wang Yanfei,Yan Bingchuan.Observation of the efficacy of adreno-corticosteroid in 21 adult patients with generalized myasthenia gravis[J].Chinese Journal of Practical Neruous Diseases,2006,9(6):44-45. |
| |
| Authors: | Zhang Kezhen Wang Yanfei Yan Bingchuan |
| |
| Abstract: | Objective To observe the efficacy,course and side effects of adreno-corticosteroid therapy in adult patients with generalized myasthenia gravis(MG).Methods Using large-dose steroids,and slowly tapering to the lowest maintainencedose,21 patients were treated.Results Steroid was effective for 100% of the patients,In initiation of steroid effects,abnormal thymus group was later than normal thymus group(P<0.01);severe generalized group was later than that of mild generalized group(P<0.01).Conclusion Adreno-corticosteroid can be used as first line drug in patients that were poorly controlled by cholinesterase inhibitors and thymectomy. |
| |
| Keywords: | Myasthenia gravis Glucocorticosteroid Efficacy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
