| B族维生素对冠心病患者血栓素B_2和6-酮-前列腺素F_(1a)的影响 |
| |
| 引用本文： | 袁宇,赵国安,谷兆侠,王卫民. B族维生素对冠心病患者血栓素B_2和6-酮-前列腺素F_(1a)的影响[J]. 新乡医学院学报, 2000, 17(2): 90-91 |
| |
| 作者姓名： | 袁宇 赵国安 谷兆侠 王卫民 |
| |
| 作者单位： | 1. 新乡医学院一附院,河南,卫辉,453100
2. 新乡医学院生物化学教研室,河南,新乡,453003 |
| |
| 基金项目： | 河南省自然科学基金资助项目(961200611) |
| |
| 摘 要： | 目的 了解B族维生素对冠心病患者血栓素B2 (TXB2 )、6 -酮 -前列腺素 (6 -K -PGF1a)的影响。方法 对 2 7例经冠状动脉造影证实的冠心病患者应用叶酸、维生素B6治疗 2wk ,采用放射免疫法测定治疗前后血浆中TXB2 、6 -K -PGF1a水平。结果 冠心病患者治疗后血浆TXB2 无明显改变 ,6 -K -PGF1a有明显升高 (P <0 .0 5 )。结论 应用B族维生素可提高 6 -K -PGF1a水平 ,改善TXB2 / 6 -K -PGF1a平衡 ,对防治冠心病具有一定价值。
|
| 关 键 词： | B族维生素 血栓素B2 6-酮-前列腺素F1a 冠心病 |
| 文章编号： | 1004-7239(2000)02-0090-02 |
| 修稿时间： | 2000-03-05 |
Influence of B - vitmins on TXB2 and 6 - K - PGF1a in patients with coronary heart disease |
| |
| YUAN Yu ,ZHAO Guo-an ,GU Zhao-xia ,WANG Wei-min. Influence of B - vitmins on TXB2 and 6 - K - PGF1a in patients with coronary heart disease[J]. Journal of Xinxiang Medical College, 2000, 17(2): 90-91 |
| |
| Authors: | YUAN Yu ZHAO Guo-an GU Zhao-xia WANG Wei-min |
| |
| Affiliation: | YUAN Yu 1,ZHAO Guo-an 1,GU Zhao-xia 2,WANG Wei-min 1 |
| |
| Abstract: | Objective To study the influence of B-vitmins on TXB 2 and 6-K-PGF 1a in patients with coronary heart disease(CHD). Methods Radioimmunoassay were used to measure the levels of TXB 2 and 6-K-PGF 1a in serum of patients with CHD undergone coronary angiography before and after of using folic acid and vitmin B 6 two weeks. Results The levels of TXB 2 were unchanged after two weeks dosing with B-vitmins,but significant increasing in 6-K-PGF 1a (P<0.05). Conclusions Application of B-vitmins will increase the level of 6-k-PGF 1a and improve the ratio of TXB 2 to 6-K-PGF 1a and confers some degree therapeutic and preventive value for CHD. |
| |
| Keywords: | B-vitmins thromboxane B 2 6-keto-prostaglandin F 1a coronary heart disease |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
