非水电位滴定法测定盐酸莫西沙星含量的方法研究 |
| |
引用本文: | 聂忠莉,李长生,唐雪枫,陈小宁,李芳.非水电位滴定法测定盐酸莫西沙星含量的方法研究[J].基层医学论坛,2013(31):4084-4086. |
| |
作者姓名: | 聂忠莉 李长生 唐雪枫 陈小宁 李芳 |
| |
作者单位: | [1]成都大学生物产业学院,四川成都610106 [2]成都欣捷高新技术开发有限公司,四川成都610041 [3]自贡市第四人民医院,四川自贡643000 |
| |
摘 要: | 目的探究非水电位滴定法降发美.分析化学M].第6版.北京:人民卫生出版社,2007:152—179.]测定盐酸莫西沙星含量的方法。方法以0.01mol/L盐酸溶液一无水甲醇(1:8)为溶剂,用甲醇钠滴定液(O.1mol/L)进行滴定。结果非水电位滴定法:方法精密度RSD为0.46%(n=9),平均回收率为100.O%。结论非水电位滴定法的测定结果与高效液相色谱法在统计学上无显著性差异,方法简便快速,结果准确可靠。
|
关 键 词: | 盐酸莫西沙星 含量 非水电位滴定法 对比研究 |
Determination of moxifloxacin hydroclfloridum standard by non-aqueous potentiometry titration |
| |
Institution: | Nie Zhongli 1,Li Changsheng 2,Tang Xuefeng 2,et al.(1 School of Bioindustry of Chengdu University,Chengdu, Sichuan 610106;2 Chengdu X injie H i-tech Development Co., Ltd., Chengdu, Sichuan 610041) |
| |
Abstract: | Objective To establish a non-aqueous potentiometry titration method for the content determination of moxifloxacin hydrochloridum standard. Methods 0.01 mol'L-1 solution of hydrochloric acid-anhydrous methanol (1: 8 ) were used as solvent for non-aqueous potentiomerry titration. 0.1 tool·L-1 solution of sodium methylate was used to titrate the content of moxifloxacin hydrochloridum standard.Results Non-aqueous Potentiometry titration: The precision RSD was 0.46 % (n = 9 ), the average recovery was 100.0%. Conclusion Non-aqueous potentimetry titration method is identical statistically. Non-aqueous potentiometry titration method is accurate and used widely. |
| |
Keywords: | Moxifloxaein hydrochloridum Content Non-aqueous potentiometry titration Contrastive study |
本文献已被 维普 等数据库收录! |
|