Unraveling galectin-1 as a novel therapeutic target for cancer期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Unraveling galectin-1 as a novel therapeutic target for cancer

Authors:	Lucile Astorgues-Xerri,Maria E. Riveiro,Annemilaï Tijeras-Raballand,Maria Serova,Cindy Neuzillet,Sé bastien Albert,Eric Raymond,Sandrine Faivre

Affiliation:	1. Oncology Therapeutic Development, 100 rue Martre, 92110 Clichy, France;2. AAREC Filia Research, 1 place Paul Verlaine, 92100 Boulogne-Billancourt, France;3. INSERM U728, Department of Medical Oncology, Beaujon University Hospital (AP-HP – Paris 7 Diderot), 100 boulevard du Général Leclerc, 92110 Clichy, France

Abstract:

Keywords:	Gal-1, galectin-1 PI3K, phosphoinositide-3-kinase MEK, mitogen-activated protein kinase kinase (MAP2K) ERK, extracellular-signal-regulated kinase ECM, extracellular matrix MMP, matrix metalloproteinase tPA, tissue plasminogen activator CDC42, cell division control protein 42 homolog RhoA, Ras homolog gene family, member A PKC, protein kinase C JNK, c-Jun NH2-terminal kinases NRP1, neuropilin-1 VEGFR2, vascular endothelial growth factor receptor 2 ROS, reactive oxygen species NFkB, nuclear factor kappa B HIF1α, hypoxia-inducible factor 1-alpha
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