Photodynamic therapy of malignant brain tumours: A complementary approach to conventional therapies |
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| Authors: | Denise Bechet,Serge R. Mordon,Franç ois Guillemin,Muriel A. Barberi-Heyob |
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| Affiliation: | 1. CRAN, Centre de Recherche en Automatique de Nancy, UMR 7039 CNRS, Université de Lorraine, Centre Alexis Vautrin, Brabois, Vandœuvre-lès-Nancy, France;2. INSERM U703, Lille University Hospital, Lille, France;3. GDR 3049 “Médicaments Photoactivables – Photochimiothérapie (PHOTOMED)”, France |
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| Abstract: | The poor outcome of primary malignant brain tumours is predominantly due to local invasion and local recurrence and their prognosis is highly dependent on the degree of resection. They have no border and, at best, a marginal zone that remains invisible to the surgeon. Photodynamic therapy (PDT) appears to be an interesting modality to fill the need for a targeted treatment that may reduce recurrence and extend survival with minimal side effects. |
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| Keywords: | Brain tumors Photodynamic therapy Fluorescence-guided resection Interventional MRI Clinical Pre-clinical Nanoparticles |
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