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Diagnóstico posparto de la enfermedad de Wilson en gestante con síndrome HELLP y coagulopatía
Authors:Marí  a Teresa Merino Ramí  rez,Marí  a Trapero Marugá  n,Marina Ronchas Martí  nez,Consuelo Villalobos Becares,Enrique Iglesias Goy
Affiliation:1. Servicio de Obstetricia y Ginecología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España;2. Servicio de Aparato Digestivo, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España
Abstract:HELLP syndrome is a clinical-analytical entity defined by microangiopathic hemolytic anemia, elevated liver enzymes, and thrombocytopenia. Liver involvement in this syndrome is common to several liver diseases. Some of these liver diseases are inherent to pregnancy (acute fatty liver of pregnancy, gestational intrahepatic cholestasis), while others are related to intercurrent disease (acute viral hepatitis) or to previous chronic liver disease. We report a case of postpartum diagnosis of chronic liver disease secondary to Wilson disease, with onset in the third trimester of pregnancy and HELLP syndrome associated with acute liver failure and coagulopathy. We review the differential diagnosis and the scientific literature on the topic.
Keywords:  ndrome HELLP    gado graso agudo   Colestasis intrahepá  tica gestacional   Enfermedad de Wilson   Embarazo   Insuficiencia hepá  tica aguda
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