Evolución clínica y paraclínica de 9 embarazos en 4 pacientes con enfermedad de Gaucher tipo 1 en el servicio de hematología de un hospital docente asistencial |
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Authors: | Ivan Alfredo Perdomo Amar,Marí a Helena Solano Trujillo |
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Affiliation: | Departamento de Hematología, Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, Colombia |
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Abstract: | ObjectivesTo describe the clinical presentation and course in a group of pregnant women with Gaucher disease type 1.Subjects and methodsPregnant women admitted to our hematology service with a medical diagnosis of Gaucher disease type 1.ResultsAll patients were classified as high risk. We describe 9 pregnancies in 4 patients: 7 were on enzyme replacement therapy before the pregnancy and continued to receive this therapy throughout the pregnancy; 1 patient discontinued therapy 8 months previously and had a hematological exacerbation.ConclusionsPregnancy should not be contraindicated in patients with stable disease. Enzyme replacement therapy should not be interrupted or suspended because it decreases complications. |
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Keywords: | Enfermedad Gaucher Embarazo Imiglucerasa Terapia de reemplazo |
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