| PAF受体拮抗剂的研究进展 |
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| 引用本文： | 王秋月,董亮,王曼丽,陈国良.PAF受体拮抗剂的研究进展[J].沈阳药科大学学报,2011,28(3):245-252. |
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| 作者姓名： | 王秋月 董亮 王曼丽 陈国良 |
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| 作者单位： | （1.沈阳药科大学 制药工程学院,辽宁 沈阳 110016; 2.中国石油新疆油田公司明园职工医院,新疆 乌鲁木齐 830000） |
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| 摘 要： | 目的综述血小板活化因子(platelet activating factor,PAF)受体拮抗剂的研究进展。方法根据已报道的介绍PAF及PAF受体拮抗剂的相关文献,将诸多PAF受体拮抗剂分为天然及合成2类,合成类再按结构分相关类别具体介绍。结果 PAF参与人体很多生理活动,异常途径生成的PAF会引起很多疾病的发生,归纳总结迄今为止研发的多种PAF受体拮抗剂。结论为PAF受体拮抗剂进一步的研究提供参考。
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| 关 键 词： | 血小板活化因子 血小板活化因子受体拮抗剂 抗炎 抗血栓 抗哮喘 |
| 收稿时间： | 2010-9-27 |
Research progress of the PAF receptor antagonists |
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| WANG Qiu-yue,DONG Liang,WANG Man-Li,CHEN Guo-liang.Research progress of the PAF receptor antagonists[J].Journal of Shenyang Pharmaceutical University,2011,28(3):245-252. |
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| Authors: | WANG Qiu-yue DONG Liang WANG Man-Li CHEN Guo-liang |
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| Institution: | WANG Qiu-yue1,DONG Liang1,WANG Man-Li2,CHEN Guo-liang1(1.School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang 110016,China,2.Mingyuan Staff-Worker Hospital of Xinjiang Oil Field Company,Urumqi 830000,China) |
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| Abstract: | Objective To review the recent developments in the research of platelet activating factor (PAF) receptor antagonists. Methods According to references about PAF and PAF receptor antagonists, the compounds were divided into natural and synthetic products, and the synthetic products were divided into sub-categories by their structures. Results PAF is involved in many physiological activities, but the PAF generated from abnormal ways may cause many diseases. Conclusions This article will provide references for the further research. |
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| Keywords: | platelet activating factor" target="_blank">platelet activating factor')">platelet activating factor platelet activating factor receptor antagonist anti-inflammatory anti-thrombotic anti-asthma" target="_blank">')">anti-asthma |
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