清热凉血法治疗大面积烧伤早期高凝状态的临床研究

目的探讨应用清热凉血法对大面积烧伤早期高凝状态（热毒血瘀型）的临床治疗作用。方法本研究分为对照组，常规治疗组及中药治疗组。对照组为正常健康献血者；常规治疗组为大面积烧伤高凝状态（热毒血瘀型）者，患者采用常规治疗；中药治疗组为大面积烧伤高凝状态（热毒血瘀型）者，患者入院后在采用常规治疗的基础上每日服用血府逐瘀汤一剂。常规治疗组及中药治疗组于伤后第3、6天取血测定活化部分凝血活酶时间（APTT）、抗凝血酶Ⅲ抗原（AT-Ⅲ：Ag，）、蛋白C活性（PC：a，）；血浆B-血小板球蛋白（β-TG）和血小板第四因子（PF4）、纤维蛋白肽（FPA）、组织纤溶酶原激活物活性（t-PA：a）。结果常规治疗组及中药治疗组与对照组相比均存在高凝状态，而中药治疗组与常规治疗组相比凝血系统功能下降，抗凝系统功能和水平改善，血小板系统活化及释放功能明显下降，纤溶能力增强。结论清热凉血法对大面积烧伤高凝状态（热毒血瘀型）的临床治疗有积极作用。

Qingrejliangxue method with hypercoagulability in massive burn patients

Objective To study the treatment effects of the Qingrejliangxue method with hypercoagulability on massive burn patients. Methods Control group were the healthy persons, routine treatment group were massive burn patients with hypercoagulability of by routine treatment, Chinese medicinal group were massive burn patients with hypercoagulability by Xuefuzhuyu decoction. Chinese medicine was taken orally in Chinese medicinal group, once a day. On the third and sixth day, prothrombin activated partial thromboplas...