| 中国2009年Ⅰ型脊髓灰质炎病毒基因特征分析 |
| |
| 引用本文： | 安军静,朱晖,严冬梅,张勇,王冬艳,祝双利,许文波. 中国2009年Ⅰ型脊髓灰质炎病毒基因特征分析[J]. 中国疫苗和免疫, 2010, 0(2) |
| |
| 作者姓名： | 安军静 朱晖 严冬梅 张勇 王冬艳 祝双利 许文波 |
| |
| 作者单位： | 中国疾病预防控制中心病毒病预防控制所病毒基因工程国家重点实验室;世界卫生组织西太平洋区脊髓灰质炎参比实验室; |
| |
| 基金项目： | 科学技术部科技支撑传染病及病媒生物控制适宜技术研究——维持无脊髓灰质炎时期外环境脊髓灰质炎病毒检测技术的建立及推广应用(2008BA156B0); 科学技术部(艾滋病和病毒性肝炎等重大传染病防治科学技术重大专项)病原体网络化监测技术研究——传染病传播的相关环境因素监测和预警框架系统(2008ZX10402) |
| |
| 摘 要： |
|
| 关 键 词： | Ⅰ型脊髓灰质炎病毒 VP1编码区 基因特征 |
Analysis on Genetic Characteristic of Type I Poliovirus in China in 2009 |
| |
| AN Jun-jing,ZHU Hui,YAN Dong-mei,et al.. Analysis on Genetic Characteristic of Type I Poliovirus in China in 2009[J]. Chinese Journal of Vaccines and Immunization, 2010, 0(2) |
| |
| Authors: | AN Jun-jing ZHU Hui YAN Dong-mei et al. |
| |
| Affiliation: | AN Jun-jing,ZHU Hui,YAN Dong-mei,et al.(World Health Organization Western Pacific Region Regional Reference Polio Laboratory,State Key Laboratory for Molecular Virology&Genetic Engineering,Institute for Viral Disease Control , Prevention,Chinese Center for Disease Control , Prevention,Beijing 100050,China) |
| |
| Abstract: | Objective To study the molecular characteristics of type 1 poliovirus isolated from the acute flaccid paralysi(sAFP)surveillance system in China in 2009,to provide a scientific basis for maintaining polio-free status for China.Method Polymerase chain reaction(RT-PCR)method was used to amplify the VP1 code region of all the type I poliovirus,and the VP1 coding region of the isolated stains was sequenced and analyzed,the hot-spots and nuerovirulence determinant were analyzed.The phylogenetic tree was construc... |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
|
