| 齐拉西酮和喹硫平对女性精神分裂症患者代谢综合征患病率的影响 |
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| 引用本文： | 李雅忠,李志猛,刘海军,杨杰.齐拉西酮和喹硫平对女性精神分裂症患者代谢综合征患病率的影响[J].中国健康心理学杂志,2012(9):1306-1308. |
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| 作者姓名： | 李雅忠 李志猛 刘海军 杨杰 |
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| 作者单位： | 河北省唐山市第五医院; |
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| 摘 要： | 目的探讨和分析齐拉西酮与喹硫平对女性精神分裂症患者代谢综合征患病率的影响。方法将符合入组标准的68例女性精神分裂症患者随机分为两组,每组各34例。分别于治疗前、治疗后1个月和3个月测定体重指数(BMI)、腰围、血压、空腹血糖(FBS)、甘油三酯(TG)和高密度脂蛋白(HDL-C),并进行比较分析。结果齐拉西酮组和喹硫平组代谢综合征的发病率分别为5.88%和21.05%。结论齐拉西酮治疗女性精神分裂症患者,发生代谢综合征的风险低于喹硫平。
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| 关 键 词： | 齐拉西酮 喹硫平 女性 精神分裂症 代谢综合征 |
The Effect of Ziprasidone and Quetiapine on Metabolic Syndrome of Female Patients with Schizophrenia |
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| Institution: | Li Yazhong,Li Zhimeng,Liu Haijun,et al.The Fifth Hospital of Tangshan,Tangshan 063000,P.R.China |
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| Abstract: | Objective To study and analyze the effect of Ziprasidone and Quetiapine on metabolic syndrome of female patients with schizophrenia.Methods A total of 68 female patients diagnosed with schizophrenia were randomly divided into two groups-one group were to be treated with Ziprasidone and the other with Quetiapine.The Body mass index（BMI）,waist circumference,blood pressure,fasting blood sugar（FBS）,triglycerides（TG）and high density lipoprotein（HDL-C）of each group were tested,compared and analyzed before the treatment,after a month and three months of treatment.Results The group treated with Ziprasidone had a risk of 5.88% getting metabolic syndrome while the group treated with Quetiapine had a risk of 21.05%.Conclusion The group treated with Ziprasidone has a lower risk of getting metabolic syndrome than that treated with Quetiapine. |
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| Keywords: | Ziprasidone Quetiapine Female Schizophrenia Metabolic syndrome |
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