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鞭打绣球的化学成分研究
引用本文:田亮,周金云.鞭打绣球的化学成分研究[J].中国中药杂志,2004,29(6):528-531.
作者姓名:田亮  周金云
作者单位:中国医学科学院,中国协和医科大学药物研究所,北京,100050
摘    要:目的 :研究鞭打绣球的化学成分。方法 :应用硅胶、SephadexLH - 2 0柱 ,制备液相进行分离、纯化 ,根据理化性质和光谱数据确定化合物的结构。结果 :分离得到 8个化合物 :鞭打绣球苷C(hemiphrosideC ,Ⅰ ) ,plan tainosideE(Ⅱ ) ,鞭打绣球苷A(hemiphrosideA ,Ⅲ ) ,acetoside(Ⅳ ) ,globularin(Ⅴ ) ,10 (Z) cinnamoyl catapol(Ⅵ ) ,iso scrophularioside(Ⅶ ) ,肉桂酸 (cinnamicacid ,Ⅷ )。结论 :化合物Ⅰ为新的苯乙醇苷 ,化合物Ⅱ ,Ⅳ为首次从鞭打绣球中分离得到。

关 键 词:鞭打绣球  化学成分  环烯醚萜苷  苯乙醇苷  鞭打绣球苷C
文章编号:1001-5302(2004)06-0528-04
收稿时间:2003/9/10 0:00:00

Studies on chemical constituents from herb of MHemiphragma heterophyllum
TIAN Liang;ZHOU Jin-yun.Studies on chemical constituents from herb of MHemiphragma heterophyllum[J].China Journal of Chinese Materia Medica,2004,29(6):528-531.
Authors:TIAN Liang;ZHOU Jin-yun
Institution:Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Abstract:OBJECTIVE: To study the chemical constituents from Hemiphragma heterophyllum. METHOD: The constituents were isolated and purified by chromatographic technology and their structures were elucidated by physico-chemical evidence and spectral data. RESULT: Eight compounds were isolated and identified as hemiphroside C (I), plantainoside E (II), hemiphroside A (III), acetoside (IV), globularin (V), 10-(Z)-cinnamoyl-catapol (VI), iso-scrophularioside (VII), cinnamic acid (VIII). CONCLUSION: Compound I was a new phenylethanoid glucoside and compounds II and VI were isolated for the first time from this plant.
Keywords:Hemiphragma heterophyllum  chemical constituents  irridoid glucoside  phenylethanoid glucoside  hemiphroside C
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