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DLF方案化疗对食管癌患者生活质量的影响
引用本文:张从军,钱勇,马越峰,陈振东. DLF方案化疗对食管癌患者生活质量的影响[J]. 现代肿瘤医学, 2007, 15(2): 209-211
作者姓名:张从军  钱勇  马越峰  陈振东
作者单位:安徽医科大学附属医院肿瘤内科,安徽,合肥,230022
摘    要:目的观察DLF方案化疗对食管癌患者生活质量的影响。方法运用EORTCQLQ-C30量表和食管癌专用量表QLQ-OES18测量DLF方案化疗前后食管癌患者生活质量的变化。结果吞咽困难、反流、疼痛等化疗后得分下降,说明化疗后生活质量改善;躯体功能、认知功能、情绪功能、总体生活质量等化疗后第2天得分下降,而到第2疗程前得分增高,恶心呕吐、疲乏、食欲减低等化疗后第2天得分增高,而到第2疗程后得分下降,化疗后患者无生活质量下降。结论DLF方案化疗能够改善食管癌患者生活质量。

关 键 词:食管癌  生活质量  化疗
文章编号:23724944
修稿时间:2006-06-08

Effect of DLF regimen chemotherapy on quality of life(QOL) in patients with esophageal cancer
ZHANG Cong-jun,QIAN Yong,MA Yue-feng,CHEN Zhen-dong. Effect of DLF regimen chemotherapy on quality of life(QOL) in patients with esophageal cancer[J]. Journal of Modern Oncology, 2007, 15(2): 209-211
Authors:ZHANG Cong-jun  QIAN Yong  MA Yue-feng  CHEN Zhen-dong
Affiliation:Department of Cancer Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
Abstract:Objective: To investigate the effect of DLF regimen chemotherapy on quality of life(QOL) in patients with esophageal cancer. Methods: All eligible patients were enrolled.The EORTC quality of life questionnaire(QLQ)-C30 and QLQ-OES18 were used to measure changes in QOL before and after the chemotherapy. Results: The mean scores such as OESDYS,OESRFX and PA decreased after the chemotherapy;the mean scores such as PF,CF,EF and global QOL decreased the second day after the chemotherapy,but before the second chemotherapy the mean scores these increased;the mean scores such as NV,FA and AP increased the second day after the chemotherapy,but before the second chemotherapy the meam scores decreased. Conclusion: DLF regimen chemotherapy improved QOL in patients with esophageal cancer.
Keywords:esophageal cancer  quality of life(QOL)  chemotherapy
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