| 正交试验优选盐炙续断炮制工艺 |
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| 引用本文： | 张丹,颜学伟,王刚,许秋霞,曹纬国,聂娟,谢智深.正交试验优选盐炙续断炮制工艺[J].中国实验方剂学杂志,2012,18(7):27-29. |
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| 作者姓名： | 张丹 颜学伟 王刚 许秋霞 曹纬国 聂娟 谢智深 |
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| 作者单位： | 1. 重庆医科大学中医药学院,重庆,401331
2. 重庆医科大学中医药学院,重庆401331;重庆医科大学中医药研究室,重庆400016;重庆医科大学中医药实验教学中心,重庆401331 |
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| 基金项目： | 重庆市卫生局科研项目(2010-1-146);重庆市渝中区科技创新项目(20100208) |
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| 摘 要： | 目的:研究盐炙工艺对川续断皂苷Ⅵ含量的影响,优选盐炙续断炮制工艺.方法:以HPLC测定川续断皂苷Ⅵ含量为评价指标,采用正交试验法筛选盐炙续断炮制工艺参数.结果:优选的盐炙续断炮制工艺为每500 g续断药材用10 g盐浸润45 min,150℃炒制8 min.结论:优选的盐炙续断炮制工艺可明显提高续断有效成分的溶出率,且工艺稳定、质量可控,为续断炮制规范的研究提供参考.
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| 关 键 词： | 盐炙续断 川续断皂苷Ⅵ 高效液相色谱法 正交试验 |
| 收稿时间： | 2011/10/31 0:00:00 |
Optimization of Processing Technology of Salt Fried Dipsacus asperoids by Orthogonal Experiment |
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| ZHANG Dan,YAN Xue-wei,WANG Gang,XU Qiu-xi,CAO Wei-guo,NIE Juan and XIE Zhi-shen.Optimization of Processing Technology of Salt Fried Dipsacus asperoids by Orthogonal Experiment[J].China Journal of Experimental Traditional Medical Formulae,2012,18(7):27-29. |
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| Authors: | ZHANG Dan YAN Xue-wei WANG Gang XU Qiu-xi CAO Wei-guo NIE Juan and XIE Zhi-shen |
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| Institution: | Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China;Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China;Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China;Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China;Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China; Lab of TCM, Chongqing University of Medical Sciences, Chongqing 400016, China; TCM Experimental Teaching Center, Chongqing University of Medical Sciences, Chongqing 401331, China;Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China;Traditional Chinaese Medicine(TCM) College, Chongqing University of Medical Sciences, Chongqing 401331, China |
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| Abstract: | Objective:To optimize processing technology of salt fried Dipsacus asperoids,study on effect of salt fried technology on the content of asperosaponin Ⅵ.Method: Orthogonal experiment was used to select processing technology parameters of salt fried D.asperoids with asperosaponin Ⅵ as evaluation index.Result: Optimal processing technology was:D.asperoids 500 g was soaked with 10 g salt for 45 min,roasted 8 min at 150 ℃.Conclusion: Optimized processing technology of salt fried D.asperoids could significantly enhance dissolution rate of effective constituent,this process was stable and quality was easy to be controlled,this research could refer to processing standards of D.asperoids. |
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| Keywords: | salt fried Dipsacus asperoids asperosaponin Ⅵ HPLC orthogonal experiment |
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