无创正压通气（NPPV）治疗急性左心衰临床效果研究

目的探讨无创正压通气治疗急性左心衰的疗效。方法选择经常规治疗疗效不佳的急性左心衰患者22例,在常规治疗基础上,辅以无创正压通气治疗。观察治疗后30m,2h,24h患者心率、呼吸频率、中心静脉压、中心静脉血氧饱和度、氧合指数、BNP的变化。结果经过治疗后患者CVP由入院时的（24±5）mmHg,下降到（15±3）mmHg;氧合指数由（135±20）增加到（390±33）;BNP由（436±56）pg/mL下降到（167±42）pg/mL。其余相关指标也明显改善。结论应用无创正压机械通气是治疗急性左心衰的一种快速有效的方法。

Clinical Observation of Non-invasive Mechanical Ventilation to Treat the Acute Left Ventricular Failure

Objective To evaluate the efficacy of noninvasive positive pressure ventilation in treating acute left ventricular failure. Methods 22 cases of the poor by conventional therapy in patients with acute left ventricular failure on the basis of conventional therapy, supplemented by non-invasive positive pressure ventilation in the treatment of acute left ventricular failure. After treat- ment, 30m, 2h, 24h heart rate, respiratory rate, central venous pressure （CVP）, central venous oxygen saturation （SCVO2）, oxygena- tion index （PO2/FIO2）, BNP. Results After treatment, improvements of relevant indicators were significantly improved. Conclusion Noninvasive positive pressure ventilation is a fast and effective method for the treatment of acute left ventricular failure.