高压氧、地塞米松治疗小儿化脓性脑膜炎疗效研究

目的:探讨高压氧、地塞米松治疗小儿化脓性脑膜炎的临床疗效,为临床上治疗小儿化脓性脑膜炎提高指导。方法:入选2009年2月～2011年9月在我院住院治疗的化脓性脑膜炎患儿147例,根据患儿治疗过程中是否选择激素治疗将其分为治疗组(n=73)和对照组(n=74)比较两组患儿治疗结果。49例患儿选择高压氧治疗,分析其临床效果。结果:治疗后,采用地塞米松治疗组患儿结果优于对照组;49例患儿接受高压氧治疗后,均全部康复出院,无1例出现后遗症;而未接受高压氧治疗的98例患儿中3例(3.1﹪)出现耳聋、智力减退等后遗症,二者相比,x2=4.562,P<0.05。结论:辅助地塞米松治疗小儿化脓性脑膜炎可以提高临床疗效,而采用高压氧治疗则可以改善患儿预后。

Clinical effects of hyperbaric oxygen and dexamethasone in pediatric patients with suppurative meningitis

Objective: To investigate the clinical effects of hyperbaric oxygen and dexamethasone in pediatric patients with suppurative meningitis.Methods: A total of 147 pediatric patients with suppurative meningitis that were treated in our hospital from February 2009 to September 2011 were enrolled and divided into treatment group(n=73) and control group(n=74),the treatment group was given dexamethasone,while the control group was treated with hyperbaric oxygen,the clinical effect were analyzed.Results: The clinical effect of the treatment group was better than that of the control group.49 patients that underwent hyperbaric oxygen therapy all recovered,while 3 cases(3.1﹪) that was not given hyperbaric oxygen got deaf or hypophrenia showing significant difference between the two(χ2=4.562,P<0.05).Conclusion: Dexamethasone can improve the clinical therapeutic effects in pediatric patients with suppurative meningitis while hyperbaric oxygen can improve the prognosis.