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Reduced docosahexaenoic acid synthesis may contribute to growth restriction in infants born to mothers who smoke |
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| Authors: | Agostoni Carlo Galli Claudio Riva Enrica Colombo Claudio Giovannini Marcello Marangoni Franca |
| Institution: | Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy. carlo.agostoni@unimi.it |
| Abstract: | In newborn infants, progressive decrease in anthropometric values and impairment of the docosahexaenoic acid (DHA) status was associated with maternal smoking during pregnancy, with a parallel increase of the metabolic precursor of DHA, alpha-linolenic acid. Maternal smoking may impair DHA synthesis which may contribute to reduced fetal growth. |
| Keywords: | ALA Alpha-linolenic acid C18:3n-3 ARA Arachidonic acid C20:4n-6 DHA Docosahexaenoic acid C22:6n-3 FA Fatty acids LA Linoleic acid C18:2n-6 LCPUFA Long-chain polyunsaturated fatty acids |
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