| IL-10及其在器官移植中的应用 |
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| 引用本文： | 唐春华,凌建煜. IL-10及其在器官移植中的应用[J]. 上海交通大学学报(医学版), 2006, 26(6): 699-700,F0003 |
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| 作者姓名： | 唐春华 凌建煜 |
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| 作者单位： | 上海交通大学医学院仁济医院器官移植中心 上海200127 |
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| 摘 要： | 白细胞介素-10(IL-10)是一种很重要的免疫调节细胞因子,近年来已成为科研热点。目前,重组人IL-10已能合成并应用于临床,主要针对类风湿关节炎、肠道炎症性病变、银屑病、乙肝等的治疗。在器官移植中,IL-10的应用也取得了相当大进展。本文就IL-10的结构、生物学功能及其在器官移植方面的临床应用等作一概述。
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| 关 键 词： | IL-10 生物学功能 器官移植 临床应用 |
| 文章编号： | 0258-5898（2006）06-0699-03 |
| 收稿时间： | 2006-02-24 |
| 修稿时间： | 2006-02-24 |
Clinical Application of IL-10 in Transplantation |
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| TANG Chun-hua,LING Jian-yu. Clinical Application of IL-10 in Transplantation[J]. Journal of Shanghai Jiaotong University:Medical Science, 2006, 26(6): 699-700,F0003 |
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| Authors: | TANG Chun-hua LING Jian-yu |
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| Affiliation: | Center of Organ Transplantation, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China |
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| Abstract: | Interleukin-10(IL-10) is a significant immunoregulatory cytokine,which has been the focus in scientific research.Recently,recombinant human IL-10 has been synthesized and is being tested in rheumatoid arthritis,inflammatory bowel disease,psoriasis,organ transplantation,and chronic hepatitis B.Great progresses have been made in IL-10 research in transplantation.This article reviews the structure,immunobiology and clinical application in transplantation of IL-10. |
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| Keywords: | IL-10 immunobiology organ transplantation clinical application |
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