糖化血红蛋白联合空腹血糖检测在妊娠期糖尿病筛查中的应用价值

目的:探讨糖化血红蛋白与空腹血糖两种方式联合检查对妊娠期糖尿病筛查的有效性.方法:选取2014至2015年在我院检查的孕妇582例,选取其中检查出妊娠期糖尿病的患者50例为观察组,同时选择同期检查的健康孕妇50例作为对照组,对比两组患者的糖化血红蛋白与空腹血糖水平,同时分析两种检查方式对受检者妊娠期糖尿病的筛查结果.结果:观察组患者血清糖化血红蛋白与空腹血糖水平均明显高于对照组(P<0.05).空腹血糖对妊娠期糖尿病的阴性预测值为43.16%,阳性预测值为92.38%,特异性为97.16%,准确性81.25%,灵敏度为43.36%;糖化血红蛋白对妊娠期糖尿病的阴性预测值为81.97%,阳性预测值为94.74%,特异性为98.25%,准确性93.16%,灵敏度为82.25%.结论:糖化血红蛋白检查妊娠期糖尿病的阴性预测值、准确性及灵敏度均明显高于空腹血糖,两种方式联合检查可以作为妊娠期糖尿病的良好筛查方法.

Glycated Hemoglobin Joint fasting Glucose Detection Application Value in Screening for Gestational Diabetes

Objective:To study the a1c and fasting plasma glucose in two ways the effectiveness of the joint inspection of gestational diabetes screening.Methods:Select 2014 to 2015 in our hospital examination of 582 cases of pregnant women, select the check out 50 cases of gestational diabetes patients as observation group, at the same time, choose the same check the health of pregnant women 50 cases as control group, com-pared two groups of patients with a1c and fasting plasma glucose levels, and analysis of two types of inspection to the client of gestational diabetes screening results.Results:Observation group of patients serum glycosylated hemoglobin and fasting plasma glucose levels were significantly higher than that of control group ( P < 0.05) . Negative predictive value of gestational diabetes fasting glucose was 43.16%, positive predictive value was 92. 38%, specificity of 97.16%, 81.25% accuracy, sensitivity is 43.36%;Glycated hemoglobin for gestational di-abetes negative predictive value of 81.97%, positive predictive value was 94.74%, specificity of 98.25%, 93. 16% accuracy, sensitivity of 82. 25%. Conclusion:Glycosylated hemoglobin examination negative predictive value, accuracy and sensitivity of gestational diabetes were significantly higher than that of fasting plasma glu-cose, two ways of joint inspection can be a good screening method of gestational diabetes.