欣母沛在预防和治疗宫缩乏力性产后出血的最佳时机探讨

目的:研究欣母沛在预防和治疗宫缩乏力性产后出血的最佳应用时机,为临床诊疗提供依据.方法:选取2014年2月到2016年2月我院收治的剖宫产产妇具有出血倾向者114例,将患者随机分为Ⅰ组、Ⅱ组和Ⅲ组,每组38例,Ⅰ组胎儿娩出后立即注射缩宫素和欣母沛,Ⅱ组胎儿娩出后立即注射缩宫素,有宫缩乏力时应用欣母沛,Ⅲ组胎儿娩出后立即注射缩宫素,不应用欣母沛,比较三组术中、回病房至术后2h和术后2h至产后24h出血量.结果:Ⅰ组术中出血量低于Ⅱ组和Ⅲ组,差异具有统计学意义(P<0.05),Ⅱ组和Ⅲ组术中出血量比较差异无统计学意义(P>0.05);Ⅰ组和Ⅱ组回病房至术后2h出血量低于Ⅲ组,差异具有统计学意义(P<0.05),Ⅰ组和Ⅱ组比较差异无统计学意义(P>0.05),Ⅰ组和Ⅱ组术后2h至产后24h出血量低于Ⅲ组,差异具有统计学意义(P<0.05),Ⅰ组和Ⅱ组比较差异无统计学意义(P>0.05).结论:胎儿分娩后立即注射缩宫素和欣母沛能有效降低产后出血量,是预防产后出血的最佳应用时机.

To Explore the Best time of Hemabate in Prevention and Treatment of Postpartum Hemorrhage

Objective:To study the best time of hemabate in prevention and treatment of postpartum hemorrhage, to provide basis for clinical diagnosis and treatment. Methods:114 cases of cesarean section with bleeding tendency from February 2014 to February 2016 in our hospital were selected, the patients were ran-domly divided into group Ⅰ, group Ⅱ and group Ⅲ, 38 cases in each group, group Ⅰ injection of oxytocin and hemabate immediately after fetal delivery, group Ⅱ injection of the oxytocin immediately after fetal delivery, application of hemabate when uterine atony, group Ⅲ injection of oxytocin immediately after fetal delivery, not using hemahate, the bleeding intraoperative, back to the ward to postoperative 2H and 2H to postpartum 24h were compared between the three groups. Results:The bleeding during operation of group Ⅰ significantly lower than Ⅱ group and Ⅲ group ( P < 0.05) , there were no significant amount of intraoperative blood loss in group Ⅱ and group Ⅲ ( P > 0.05);back to the ward to postoperative 2H bleeding of group Ⅰ and group Ⅱ were sig-nificantly lower than those in the group Ⅲ ( P < 0.05) , group Ⅰ and group Ⅱ were not statistically significant ( P > 0.05) , 2H to postpartum 24h bleeding of group Ⅰ and group Ⅱ were significantly lower than those in the group Ⅲ ( P < 0.05) , group Ⅰ and group Ⅱ were not statistically significant ( P > 0.05) . Conclusion:Fetal delivery immediately injection of oxytocin and Pei could effectively reduce the amount of postpartum hemor-rhage, it is the best time to prevent postpartum hemorrhage.