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毛冬青根中的新三萜皂苷
引用本文:赵钟祥,曾瑞鑫,金晶,林朝展,熊天琴,蔡金艳,祝晨蔯.毛冬青根中的新三萜皂苷[J].中草药,2012,43(7):1267-1269.
作者姓名:赵钟祥  曾瑞鑫  金晶  林朝展  熊天琴  蔡金艳  祝晨蔯
作者单位:1. 广州中医药大学中药学院,广东广州,510006
2. 中山大学药学院,广东广州,510006
3. 广东药学院药科学院,广东广州,510006
基金项目:国家自然科学基金资助项目(30901954);广东省自然科学基金资助项目(9451040701003203);高等学校博士学科点专项科研基金资助项目(20094425110008);广州市珠江科技新星专项(2011J2200047)
摘    要:目的研究毛冬青Ilex pubescens根的化学成分。方法采用硅胶、Sephadex LH-20等柱色谱法对毛冬青根中的化学成分进行分离纯化,应用谱学技术和化学方法鉴定化合物的结构。结果分离鉴定了1个三萜苷皂类化合物3-O-β-D-吡喃木糖基-3β,19α,24-三羟基齐墩果酸(1)。结论化合物1为新的化合物,命名为毛冬青皂苷D。

关 键 词:毛冬青  3-O-β-D-吡喃木糖基-3β  19α  24-三羟基齐墩果酸  毛冬青皂苷D  齐墩果酸  三萜皂苷
收稿时间:2012/4/26 0:00:00

A new triterpenoid glycoside from roots of Ilex pubescens
ZHAO Zhong-xiang,ZENG Rui-xin,JIN Jing,LIN Chao-zhan,XIONG Tian-qin,CAI Jin-yan and ZHU Chen-chen.A new triterpenoid glycoside from roots of Ilex pubescens[J].Chinese Traditional and Herbal Drugs,2012,43(7):1267-1269.
Authors:ZHAO Zhong-xiang  ZENG Rui-xin  JIN Jing  LIN Chao-zhan  XIONG Tian-qin  CAI Jin-yan and ZHU Chen-chen
Institution:1.School of Chinese Materia Medica,Guangzhou University of Chinese Medicine,Guangzhou 510006,China 2.School of Pharmaceutical Sciences,Sun Yat-Sen University,Guangzhou 510006,China 3.School of Pharmacology,Guangdong Pharmacological University,Guangzhou 510006,China
Abstract:Objective To investigate the chemical constituents from the roots of Ilex pubescens.Methods The compounds were separated and purified by chromatography on silica gel,and Sephadex LH-20 columns.Their chemical structures were elucidated on the basis of spectroscopic methods and chemical evidences.Results A triterpenoid glycoside was purified and its structure was identified as 3-O-β-D-xylopyranosylspathodic acid(1).Conclusion Compound 1 is a new triterpenoid glycoside,named ilexsaponin D.
Keywords:Ilex pubescens Hook  et Arm    3-O-β-D-xylopyranosylspathodic acid  ilexsaponin D  oleanic acid  triterpenoid glycoside
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