疏刺茄化学成分研究(Ⅰ)

目的研究疏刺茄Solanum nienkui的化学成分。方法应用硅胶柱色谱、Sephadex LH-20柱色谱、反相柱色谱及重结晶等方法分离纯化,根据理化性质和光谱数据鉴定化合物结构。结果从疏刺茄的三氯甲烷部位分离得到11个化合物,分别鉴定为7,2′,4′-三羟基-5-甲氧基异黄酮(1)、香叶木素(2)、柚皮素(3)、山柰酚(4)、槲皮素(5)、咖啡酸乙酯(6)、原儿茶醛(7)、邻羟基苯甲酸(8)、香草醛(9)、水杨酸甲酯(10)、N-p-香豆酰酪胺(11)。结论所有化合物均为首次从该植物中分离得到,化合物1为首次从茄科植物中分离得到。

Chemical constituents from Solanum nienkui (I)

Objective To study the chemical constituents from Solanum nienkui.Methods The compounds were isolated by chromatography on silica gel,Sephadex LH-20,and reverse phase column as well as recrystallisation,and their structures were identified on the basis of physicochemical characteristics and spectroscopic analyses.Results Eleven compounds were obtained from the CHCl3 extract of S.nienkui with the structures as 7,2′,4′-trihydroxys-5-methoxyisoflavanone(1),diosmetin(2),naringenin(3),kaempferol(4),quercetin(5),ethyl caffeate(6),protocatechuic aldehyde(7),o-hydroxybenzoic acid(8),vanillin(9),methylsalicylate(10),and N-p-paprazine(11).Conclusion All the compounds are isolated from this plant for the first time,and compound 1 is isolated from the plants in Solanaceae for the first time.