胸段食道癌转移患者出现肺转移的危险因素分析

目的 通过分析胸段食道癌转移患者各种临床指标及肺转移的关系，探讨他们在胸段食道癌转移与肺转移的危险预测价值。方法 回顾性分析191例胸段食道癌癌转移患者性别、年龄、吸烟、饮酒、胸段食道癌大小、癌部位、癌病理类型等各种指标水平，二项logistic回归分析它们与胸段食道癌肺转移之间的关系。结果 191例胸段食道癌转移患者中肺部转移129例（67.54％），吸烟病例为120例（62.83％）。胸段食道癌转移患者中吸烟、男性及胸部上、中段食道癌出现肺转移高于非肺转移病例（P=0.010, P=0.000及 P=0.020）。吸烟是胸段食道癌肺转移主要危险因素（P=0.004，回归系数1.037；OR值为2.821；OR值95%可信区间为1.399-5.689）。结论 胸段食道癌转移患者合并吸烟，其发生肺转移可能性显著增加。

Risk of lung metastasis from thoracic esophageal cancer with metastasis

【Abstract】 Objective To determine the risk of lung metastasis from thoracic esophageal cancer with metastasis. Method: Clinic data of 191 patients with thoracic esophageal cancer with metastasis were reviewed and risk value in lung metastasis was analyzed by logistic regression. Result We identified 191 thoracic esophageal cancer with metastasis cases; lung metastasis and smoking status was known in 129(67.54%) and 120 (62.83%) respectively. Among patients with lung metastases, smokers, male, local of up and middle thoracic esophageal cancer are more than patients without lung metastases. Smokers are the risk of lung metastasis from thoracic esophageal cancer with metastasis [P=0.004; summary odds ratio (OR), 2.821; 95% confidence interval (95% CI), 1.399-5.689]. Conclusions. Cigarette smoking may be a risk of lung metastasis from thoracic esophageal cancer with metastasis. 【key word】 Cigarette smoking; thoracic esophageal cancer; metastasis; lung metastasis; logistic regression