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淋巴细胞主动免疫联合小剂量IVIG治疗URSA的初步探讨
引用本文:崔蓉,苗竹林,赵文忠,秦卫兵,王小兰,杨宁,王一峰. 淋巴细胞主动免疫联合小剂量IVIG治疗URSA的初步探讨[J]. 中国计划生育学杂志, 2013, 21(5): 331-333
作者姓名:崔蓉  苗竹林  赵文忠  秦卫兵  王小兰  杨宁  王一峰
作者单位:崔蓉 (广东省计划生育科学技术研究所 广州,510600); 苗竹林 (广东省计划生育科学技术研究所 广州,510600); 赵文忠 (广东省计划生育科学技术研究所 广州,510600); 秦卫兵 (广东省计划生育科学技术研究所 广州,510600); 王小兰 (广东省计划生育科学技术研究所 广州,510600); 杨宁 (广东省计划生育科学技术研究所 广州,510600); 王一峰 (广东省计划生育科学技术研究所 广州,510600);
基金项目:广东省人口计生委科技项目(项目编号:20110214)广东省科技计划项目(项目编号:2011A030400011)
摘    要:目的:探讨淋巴细胞主动免疫联合静脉点滴小剂量免疫球蛋白治疗复发性流产的临床疗效。方法:经临床筛查确诊为不明原因复发性流产患者72例,分为观察组(47例,采用淋巴细胞主动免疫联合静脉点滴小剂量免疫球蛋白治疗)和对照组(25例,采用淋巴细胞主动免疫治疗),观察妊娠结局。结果:妊娠成功率观察组(89.36%)高于对照组(68.00%)(P<0.05)。结论:淋巴细胞主动免疫联合静脉点滴小剂量免疫球蛋白治疗复发性流产成功率较高,有较好的应用价值。

关 键 词:主动免疫  免疫球蛋白  复发性流产

Study on unexplained recurrent spontaneous abortion under treatment of initiative immunotherapy with lymphocytes and low-dose intravenous immunoglobulin
Cui Rong,Miao Zhulin,Zhao Wenzhong,Qin Weibin,Wang Xiaolan,Yang Ning,Wang Yifeng. Study on unexplained recurrent spontaneous abortion under treatment of initiative immunotherapy with lymphocytes and low-dose intravenous immunoglobulin[J]. Chinese Journal of Family Planning, 2013, 21(5): 331-333
Authors:Cui Rong  Miao Zhulin  Zhao Wenzhong  Qin Weibin  Wang Xiaolan  Yang Ning  Wang Yifeng
Affiliation:Guangdong Family Planning Reseach Institute, Guangzhou 510600
Abstract:Objective: To investigate the effect of initiative immunotheraphy with lymphocytes and low-dose intravenous immunoglobulin (IVIG) in women suffering from unexplained recurrent spontaneous abortion. Methods: Seventy-two patients diagnosed as unexplained recurrent spontaneous abortion were divided into two groups: the study group (n=47, in which women received initiative immunotherapy with lymphocytes and low-dose IVIG) and the control group (n=25, in which women received initiative immunotherapy only with lymphocytes). The pregnancy outcome was evaluated. Results: The pregnancy rate was 89.36% in the study group and only 68.00% in the control group, showing a significant difference between the two groups (P<0.05) . Conclusion: Initiative immunotherapy with lymphocytes and low-dose IVIG may act as an effective and safe method for treatment of unexplained recurrent spontaneous abortion.
Keywords:Initiative immunity   Immunoglobulin   Recurrent spontaneous abortion
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