武汉市妊娠期高血压疾病及其不良妊娠结局大样本流行病学分析

目的:通过流行病学分析了解武汉市妊娠期高血压疾病(PIH)及其不良妊娠结局的发生情况,进一步探讨PIH对妊娠结局的影响。方法:回顾性分析2011年武汉市83 761例孕产妇产时相关资料,分析妊娠期高血压疾病组与非妊娠期高血压疾病孕产妇的不良妊娠结局发生情况。结果:2011年武汉市共发生妊娠期高血压疾病3 064例,发生率为3.67%。城镇孕产妇发生率高于农村孕产妇,经产妇高于初产妇,多胎高于单胎,孕产妇年龄越大发生率越高,PIH孕产妇组的产后出血、胎盘早剥、新生儿窒息、早产、剖宫产、死胎、新生儿死亡及低出生体重(体重<2 500 g)的发生率明显高于非妊娠期高血压疾病孕产妇。子痫不良妊娠结局的发生率明显高于妊娠期高血压和子痫前期患者。结论;武汉市PIH发生率处于较低水平,PIH的发生与城乡、年龄、产次、多胎相关,PIH增加母婴不良妊娠结局,应加强对孕产妇保健管理,减轻PIH疾病危害,改善母婴结局,降低孕产妇和新生儿并发症及死亡率。

Large sample epidemiological analysis of pregnancy-induced hypertension and bad pregnancy outcome in Wuhan

Objective:To explore the influence of pregnancy induced hypertensive(PIH) syndrome on pregnant outcome through analyzing the incidence and adverse outcome of PIH pregnant women by epidemiologic methods.Methods:Retrospective analysis was executed.83 761 cases in Wuhan in 2011 from the local material and child healthcare information system were selected and the difference of pregnant outcome between PIH group and non-PIH group was compared.Results:There were 3 064 PIH cases among 83 761 pregnant women,the incidence rate was 3.67%,the incidence of urban pregnant women was higher than that of rural pregnant women,and multiparity was higher than that of primiparity,and multiple pregnancy was higher than that of single pregnancy.The incidence of PIH was higher along with the age of the pregnant women.The incidence of postpartum hemorrhage,placental abruption,neonatal asphyxia,premature birth,cesarean section,stillbirth,neonatal death and low birth weight of PIH was significantly higher than that of non-PIH.The incidence of adverse outcome of eclampsia was higher than that of other type of PIH.Conclusion:The incidence of PIH in Wuhan is at a low level,and the incidence is associated with area,age,multiparity and multiple pregnancy.A marked increase in adverse outcome of maternal and children can be found in PIH,so regular antenatal care should be strengthened to improve pregnant outcomes and reduce maternal and neonatal complications and mortality.