Modern Antioestrogens and the Coming Revolution in Women's Health Care |
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Authors: | Amanda Evans MRANZCOG FRACGP Beverley Vollenhoven PhD FRANZCOG CREI David Healy PhD FRANZCOG CREI |
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Affiliation: | Monash University Department of Obstetrics and Gynaecology, Monash Medical Centre, Victoria. |
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Abstract: | This review will focus on antioestrogens and selective oestrogen receptor modulators (SERMS). The more traditional SERMS, clomiphene citrate and tamoxifen, will be reviewed along with such modern drugs as raloxifene and faslodex, with emphasis upon their actions on breast, uterus, bone and lipids. The future potential of these medications, in the management of oestrogen-dependent gynaecological conditions such as endometriosis, dysfunctional uterine bleeding, fibroids and breast cancer will be discussed. |
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