| MR动态增强扫描评估正常兔肾实质的血流灌注 |
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| 引用本文： | 刘铁滨,王和平.MR动态增强扫描评估正常兔肾实质的血流灌注[J].中国现代医生,2012,50(11):53-54. |
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| 作者姓名： | 刘铁滨 王和平 |
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| 作者单位： | 湖南师范大学医学院临床医学系 |
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| 基金项目： | 湖南省教育厅课题(08C567) |
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| 摘 要： | 目的探讨动态增强磁共振检查对正常肾实质血流灌注评价的作用。方法健康大白兔9只,行肾脏动态增强MR检查,测量各肾皮质及髓质的信号强度,绘出其平均信号强度-时间曲线,记录皮质、髓质的平均峰值（P）及峰值/达峰时间比（P/T）。结果肾脏的灌注曲线（SI-T曲线）稳定,获得的血流灌注参数（Pc,Pm,Pc/Tc,Pm/Tm）具有一定规律,MR动态增强可反映出肾实质的血流动力学状态。结论动态增强MR能够反映肾脏血流灌注的变化,为兔肾血流动力学研究提供新的无创性手段。
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| 关 键 词： | 磁共振成像 肾脏灌注 血流动力学 |
Evaluation of renal blood perfusion in healthy rabbits with enhanced dynamic magnetic resonance |
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| Authors: | LIU Tiebin WANG Heping |
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| Institution: | Department of Cilincal Medicine,Medical College in Hunan Normal University,Changsha 410013,China |
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| Abstract: | Objective To evaluate the renal blood perfusion in the healthy rabbits with dynamic contrast-enhanced MR technology.Methods Dynamic contrast-enhanced MR was performed in 9 healthy rabbits to obtain the mean signal intensity-time curves of both cortex and medulla of each kidney.Mean peak intensity value(P) and the P/Time to peak ratio at the cortex and medulla(Pc,Pm,Pc/Tc,Pm/Tm)of each kidney were measured.Results The renal perfusion curves(signal intensity time curve,SI-T curve)were stabl,and regularity was revealed in the blood perfusion parameters(Pc、Pm、Pc/Tc、Pm/Tm).The renal hemodynamic information could be obtained with dynamic contrast-enhanced MR technology.Conclusion Dynamic contrast-enhanced MR scan can be used to assess the change of renal blood perfusion and provide new imaging methods for measuring the renal hemodynamics in healthy rabbits. |
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| Keywords: | Magnetic resonance imaging Renal perfusion Hemodynamics |
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