| 老年高血压病患者脂联素与白细胞介素-6、超敏C反应蛋白的相关性研究 |
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| 引用本文： | 钟伟,李章白,廖雪梅,李家富.老年高血压病患者脂联素与白细胞介素-6、超敏C反应蛋白的相关性研究[J].疑难病杂志,2011,10(7):487-489. |
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| 作者姓名： | 钟伟 李章白 廖雪梅 李家富 |
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| 作者单位： | 1. 重庆市荣昌县人民医院心内科,402460
2. 泸州医学院附属医院心内科,646000 |
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| 摘 要： | 目的探讨老年高血压病患者血清脂联素(APN)与白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)的相关性。方法选择老年高血压病患者(高血压病组64例,其中高血压1级亚组23例,2级亚组21例,3级亚组20例)。老年健康体检者(健康对照组25例),采用酶联免疫法测定APN、IL-6水平,免疫比浊法测定hs-CRP水平。结果高血压病组APN浓度(7.8±5.6)mg/L]低于健康对照组(9.9±3.3)mg/L](P<0.05),而IL-6水平(59.9±7.5)ng/ml]、hs-CRP水平(5.9±2.0)mg/L]高于健康对照组分别为(18.7±5.4)ng/ml和(2.4±1.4)mg/L],差异均有统计学意义(P<0.05);且高血压2级、3级亚组与1级亚组比较差异亦有统计学意义(P<0.05)。相关性分析表明,APN与IL-6、hs-CRP呈负相关(分别为r=-0.577,P<0.05;r=-0.582,P<0.05)。结论老年高血压病患者的APN降低,IL-6、hs-CRP升高,APN与IL-6、hs-CRP呈负相关。
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| 关 键 词： | 高血压病 脂联素 白细胞介素-6 超敏C反应蛋白 老年人 |
The relationship between APN and hs-CRP,IL-6 in elderly patients with essential hypertension |
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| ZHONG Wei,LI Zhang-bai,LIAO Xue-mei,et al..The relationship between APN and hs-CRP,IL-6 in elderly patients with essential hypertension[J].Journal of Difficult and Complicated Cases,2011,10(7):487-489. |
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| Authors: | ZHONG Wei LI Zhang-bai LIAO Xue-mei |
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| Institution: | ZHONG Wei,LI Zhang-bai,LIAO Xue-mei,et al.Department of Cardiology,People' s Hospital of Rongchang County,Chongqing 402460,China |
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| Abstract: | Objective To investigate the relationship between the adiponectin(APN) and hs-CRP,IL-6 in elderly patients with essential hypertension.Methods Sixty-four elderly patients with essential hypertension were enrolled the study, including 23 cases with grade 1,21 cases with grade 2,and 20 cases with grade 3,other 25 healthy elderly people were enrolled as control group.The serum levels of APN,IL-6 were measured with ELISA method,and the serum level of hs-CRP were detected by immunonephelometric method.The relati... |
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| Keywords: | Hypertension Adiponectin IL-6 hs-CRP Elderly |
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