| 5-氟尿嘧啶阴道填塞联合人白介素-2治疗宫颈尖锐湿疣49例临床观察 |
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| 引用本文： | 丁振干,汪敏,庄玮莉.5-氟尿嘧啶阴道填塞联合人白介素-2治疗宫颈尖锐湿疣49例临床观察[J].中国皮肤性病学杂志,2004,18(1):42-43. |
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| 作者姓名： | 丁振干 汪敏 庄玮莉 |
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| 作者单位： | 1. 浙江省苍南县人民医院皮肤科,浙江,苍南,325800
2. 上海第二医科大学附属宝钢医院皮肤科,上海,201900 |
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| 摘 要： | 目的 评价 5 氟尿嘧啶 (5 FU)联合人白介素 2 (IL 2 )治疗宫颈尖锐湿疣 (CA)的疗效和安全性。方法 治疗组 49例宫颈CA采用 2 .5 %的 5 FU液阴道填塞 ,1次 /d ,共 4次 ,同时肌肉注射IL 2 2 0万u ,1次 /d ,共 2周 ;对照组46例采用二氧化碳激光联合IL 2治疗 ,IL 2用法同治疗组。结果 治疗组治愈率 86.9%,对照组治愈率 45 .4%,差异有高度显著性 (P <0 .0 1)。结论 此法安全有效 ,尤其适用于无禁忌症、反复发作、采用激光等治疗有困难的宫颈CA患者。
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| 关 键 词： | 宫颈尖锐湿疣 5-氟尿嘧啶 白介素-2 |
| 文章编号： | 1001-7089(2004)01-0042-01 |
Clinical Observation of 5-Fliorouracil Combined with Interleukin-Ⅱ in the Treatment of 49 Patients with Cervial Condyloma Acuminita |
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| DING Zhen-gan,WANG Min,ZHUANG Wei-li.Clinical Observation of 5-Fliorouracil Combined with Interleukin-Ⅱ in the Treatment of 49 Patients with Cervial Condyloma Acuminita[J].The Chinese Journal of Dermatovenereology,2004,18(1):42-43. |
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| Authors: | DING Zhen-gan WANG Min ZHUANG Wei-li |
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| Abstract: | Objective To investigate the efficacy and safety of 5-Fliorouracil (5-FU) used in vagina combined with Interleukin-Ⅱ (IL-2) injection in the treatment of cervical condyloma acuminata (CA).Methods 49 patients with cervical CA in the study group were treated with 2.5% 5-FU in vagina once per day for 4 days and intramuscular injection of IL-2 (2.0×10 5 IU) once per day for two weeks.46 patients in the control group were treated with CO 2 laser and IL-2 injection. The schemes of IL-2 injection were the same in the two groups. Results The difference of cure rate was significant( P <0.01) between the study group (86.9%) and the control group (45.4%). Conclusion The treatment is effective and safe. It’s especially suitable for patients with recurrent cervical CA who have no contraindications and have difficulty in CO 2 laser therapy. |
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| Keywords: | Cervial condyloma acuminita 5-Fliorouracil Interleukin II |
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