Atrial electromechanical interval can identify patients with paroxysmal atrial fibrillation and is associated with CHADS2 score and peak velocity of left atrial appendage |
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Authors: | Chao Tze-Fan Sung Shih-Hsien Wang Kang-Ling Tsao Hsuan-Ming Lin Yenn-Jiang Chang Shih-Lin Lo Li-Wei Hu Yu-Feng Tuan Ta-Chuan Suenari Kazuyoshi Li Cheng-Hung Liu Shuen-Hsin Wu Tsu-Juey Yu Wen-Chung Chen Shih-Ann |
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Institution: | Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. |
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Abstract: | Electromechanical Interval and Paroxysmal Atrial Fibrillation . Introduction: It is difficult to discriminate patients with and without paroxysmal atrial fibrillation (PAF). The atrial electromechanical interval determined by the transthoracic echocardiogram is demonstrated to be a predictor of new onset AF. The aim of our study was to investigate whether the electromechanical interval is a useful parameter to identify patients with PAF. Methods and Results: A total of 297 patients (PAF group = 103; control group = 194) with mean age of 59.4 ± 12.4 years were enrolled. The electromechanical interval (PA‐PDI) defined as the time interval from the initiation of the P‐wave deflection to the peak of the mitral inflow A wave on the pulse‐wave Doppler imaging was measured for every patient. Patients with PAF had significantly longer PA‐PDI intervals compared with that of patients without it (152.7 ± 13.8 ms vs 133.4 ± 16.8 ms). The area under ROC curve based on the PA‐PDI interval to diagnose PAF was 0.803 (95% confidence interval = 0.755–0.851, P < 0.001). At the cut‐off value of 142 ms, the sensitivity and specificity in identifying PAF were 77.7% and 80.1%, respectively. In the PAF group, the PA‐PDI interval was closely associated with the CHADS2 score and inversely related with the peak velocity of left atrial appendage. Conclusions: The PA‐PDI interval may be a useful parameter to identify patients with PAF. Further studies are necessary to evaluate the usefulness of PA‐PDI intervals in diagnosing PAF in addition to the current methods and tools. (J Cardiovasc Electrophysiol, Vol. 22, pp. 1325‐1330, December 2011) |
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Keywords: | atrial electromechanical interval CHADS2 score left atrial appendage paroxysmal atrial fibrillation stroke |
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