2010—2011年上海市闵行区腹泻患者病原菌检测结果

目的了解上海市闵行区腹泻病原菌的分布和药物敏感情况,为临床合理用药及预防控制工作提供科学依据。方法对闵行区中心医院、市五医院及各社区卫生服务中心腹泻患者的肛拭子标本进行病原菌分离检测,并用K-B法对检测出的致病菌进行药物敏感试验。结果 2010—2011年标本共计11 035件,阳性检出率为9.41%。检出的致病菌以副溶血性弧菌为主,其次是志贺菌和沙门菌。其每年的阳性检出率分别为9.59%、9.19%。这3种致病菌对环丙沙星、庆大霉素、头孢类抗生素敏感,对利福平、萘啶酸高度耐药。结论该区腹泻患者中的致病菌以副溶血性弧菌为主,其次是志贺菌和沙门菌,有明显的季节性。根据药物敏感试验结果,应加强耐药性监测和防治,临床上使用抗菌药更应慎重。

Pathogen detection results of patients with acute diarrhea in Minhang District of Shanghai City from 2010-2011

[Objective]To understand the pathogens distribution and bacterial susceptibility of diarrhea pathogens,and provide scientific evidence for rational drug use in clinic and diarrhea prevention and control.[Methods]The pathogens collected from anal swab specimens of patients with diarrhea treated in Minhang District Central Hospital,5 municipal Hospitals and each community health center were isolated for detection. The K-B method was used for bacterial susceptibility test of isolated pathogens.[Results] A total of 11 035 samples of pathogen were detected from 2010-2011,with positive rate of 9. 41% . The main type of pathogens was Vibrio parahemolyticus,followed by Shigella and Salmonella,the positive rate was 9. 59% ,9. 19% ,respectively. The 3 pathogens were highly resistant to ciprofloxacin,gentamicin,cephalosporins,rifampin,nalidixic acid. [Conclusion]The main pathogen is Vibrio parahemolyticus in this district,followed by Shigella and Salmonella,with obviously seasonal features. According to the bacterial susceptibility test,resistance monitoring and prevention should be enhanced and the clinical use of antimicrobial drugs should be carefully.