经鼻持续气道正压通气治疗新生儿呼吸衰竭50例

目的探讨经鼻持续气道正压通气(CPAP)治疗新生儿呼吸衰竭的疗效。方法50例呼吸衰竭新生儿中,Ⅰ型呼吸衰竭23例,Ⅱ型呼吸衰竭27例,给予TCPAP治疗,观察患儿在TCPAP前、TCPAP6h后及24h后的临床及血气变化。结果50例患儿TCPAP治疗后呼吸困难及缺氧征有不同程度的好转,血气PaO2均明显提高(P<0.01),Ⅱ型呼吸衰竭患者PaCO2显著下降(P<0.01),而Ⅰ型呼吸衰竭患者PaCO2无变化。结论TCPAP可以改善氧合和通气,对I型和Ⅱ型新生儿呼衰均有疗效。

Transnasal continous positive airway pressure for the treatment of 50 cases of neonatal respiratory failure

Objective To explore the efficacy of transnasal continous positive air-way pressure (TCPAP) in treatment of neonatal respiratory failure.Methods Among 50 cases of neonatal respiratory failure(RF),23 cases were type I RF and 27 were type II RF.All patients were performed with TCPAP.Clinical symptoms and changes of PaO2 and PaCO2 before TCPAP,6 h and 24 h after TCPAP were observed respectively.Results Dyspnea and hypoxia in 50 infants treated with TCPAP improved in different degrees.PaO2 increased obviously(P<0.01).PaCO2 decreased obviously in infants with type II RF(P<0.01),however,PaCO2 had no changes in type I RF.Conclusion TCPAP can improve oxygen saturation and hypoventilation of type I and II RF.