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荧光显微镜检对吖啶橙浸染的胃癌细胞的诊断
引用本文:秦光明,马瑞君,王家. 荧光显微镜检对吖啶橙浸染的胃癌细胞的诊断[J]. 华中科技大学学报(医学版), 1987, 0(4)
作者姓名:秦光明  马瑞君  王家
作者单位:同济医科大学基础医学部组织胚胎学教研室(秦光明,马瑞君),同济医科大学附属同济医院内科(王家)
摘    要:本文对145例胃病患者(其中胃癌50例)在纤维胃镜直视下,钳取胃活体组织作印片(或涂片),用吖啶橙染色,在荧光显微镜下观察。结果与活组织学诊断比较,荧光显微镜诊断的特异性为96.0%,敏感性为96.8%。此法简单易行,取得结果迅速,是配合纤维胃镜检查对胃癌早期诊断的有效方法之一。

关 键 词:细胞诊断学  吖啶橙染色  显微镜检查  荧光  胃肿瘤

Cytological Diagnosis of Gastric Carcinoma by Fluorescence Microscopy on Acridine Orange Stained Preparations
Qin Guangming,Ma Ruijium. Cytological Diagnosis of Gastric Carcinoma by Fluorescence Microscopy on Acridine Orange Stained Preparations[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1987, 0(4)
Authors:Qin Guangming  Ma Ruijium
Affiliation:Qin Guangming,Ma RuijiumDepartment of Histology & Embryology,Faculty of Basic Medical Sciences,Tongji medical University,WuhanWang Jialong Department of Medicine,Tongji Hospital,Tongji Medical University,Wuhan
Abstract:Cytological specimens, i. e. prints or smears were prepared from fib-rogastroscopy biopsied materials from 145 patients, with various gastric diseases, including 50 cases of gastric carcinoma. The preparations were stained with acri dine orange and examined by fluorescence microscopy. The results were compared with those of histopathological observations. Out of 50 cases of gastric carcinoma, 48 cases were detected by this procedure, showing a specificity rate of 96.0% and a sensitivity rate of 96.8%. We concluded that fluorescence microscopy on acridine orange stained cytological preparations is a simple and easy procedure. It is less time consuming and should be considered to be one of the efficient diagnostic measures supplementary to fibrogastroscopy.
Keywords:cytodiagnosis  acridine orange staining  microscopy   fluorescence  stomach neoplasms
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