转化医学中利益冲突及其影响

医学、法律和伦理是相互伴生的科学.近年来,转化医学的提出及其开展,促进基础研究成果的快速的临床转化和应用,促使研究成果尽快形成市场化的产品,提高医疗诊断水平和促进健康.同时面临一些新的挑战,产生新的伦理问题,并使一些现有伦理问题更为凸显.开展转化医学具有潜在的风险和问题,利益冲突,及其对受试者权益保护和知情同意的潜在影响还没有受到应有的重视,需要伦理委员会加强审核.

Conflicts of interests and its effects on informed content,protection of human subjects in translational medicine

Medicine, law and ethics are closely related to each other. Translational medicine is a research model to promote basic research into clinical application rapidly. Its ultimate goal is to promote development of new drug and method as quickly as possible, to improve the level of clinical diagnostics and treatment for health promotion. But some new challenges we have to face in line with accelerating medical research from lab to bedside. There are some potential risk and ethical issues. Among them, conflicts of interest and its affection on implementation of informed consent and protection of human subjects has not been given sufficient attention. The conflict of interest should be managed allows people to exercise their rights as autonomous agents to make their own informed decisions and deter investigators and institutions from having significant conflicts of interest.