| 原发性肝癌患者肝组织中幽门螺杆菌的免疫组织化学观察 |
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| 引用本文： | 黄燕,范学工,周建华,田雪飞. 原发性肝癌患者肝组织中幽门螺杆菌的免疫组织化学观察[J]. 中南大学学报(医学版), 2004, 29(1): 15-17 |
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| 作者姓名： | 黄燕 范学工 周建华 田雪飞 |
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| 作者单位： | 中南大学湘雅医院感染病科,长沙,410008;中南大学湘雅医院感染病科,长沙,410008;中南大学湘雅医院感染病科,长沙,410008;中南大学湘雅医院感染病科,长沙,410008 |
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| 基金项目： | 国家自然科学基金 (3 0 2 71171)，教育部优秀骨干教师基金 (教技司 2 0 0 0 65 )，湖南省自然科学基金(0 1jjy2 114 )，湖南省卫生厅科研基金 (0 0 0 2 2 ) |
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| 摘 要： | 目的：研究肝组织中幽门螺杆菌的感染情况。方法：将38例原发性肝癌，15例肝硬化和15例肝脏良性肿瘤组织进行幽门螺杆菌的免疫组化染色。结果：38例肝癌标本中有16例（42％）观察到幽门螺杆菌的存在，而肝硬化和对照肝组织中未观察到幽门螺杆菌的存在。结论：原发性肝癌组织中存在幽门螺杆菌感染。
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| 关 键 词： | 肝肿瘤 癌 幽门螺杆菌 免疫组织化学 |
| 文章编号： | 1672-7347(2004)01-0015-03 |
| 收稿时间： | 2003-04-10 |
| 修稿时间： | 2003-04-10 |
Immunohistochemistry of Helicobacter pylori in primary liver carcinoma tissues |
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| HUANG Yan,FAN Xue-gong,ZHOU Jian-hua,et al.. Immunohistochemistry of Helicobacter pylori in primary liver carcinoma tissues[J]. Journal of Central South University. Medical sciences, 2004, 29(1): 15-17 |
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| Authors: | HUANG Yan FAN Xue-gong ZHOU Jian-hua et al. |
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| Affiliation: | Department of Infectious Disease, Xiangya Hospital,Central South University,Changsha 410008，China |
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| Abstract: | Objective To detect the infection of H. pylori in liver specimens.Methods Liver samples from 38 patients with primary liver carcinoma diagnosed by histopathology,15 with liver cirrhosis, and 15 with nonmalignant neoplasm as controls were studied. The immunohistochemical staining for H. pylori was performed. Results H. pylori was detected in 16 of the 38 liver samples (42%) of hepatocellular carcinoma, while no bacteria were found in nonmalignant liver tissues. Conclusion H. pylori may present in tissues of primary liver carcinoma and it is probably linked to carcinogenesis of liver cancer. |
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| Keywords: | liver neoplasm carcinoma Helicobacter pylori immunohistochemistry |
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