基质内角膜环植入后角膜屈光力变化实验研究

目的：观察基质内角膜环（ICR）植入术的安全性及有效性。方法：60只兔眼随机植入不同厚度的ICR,分别于术前及术后1,3天,1,2周,1,3,6月作裂隙灯检查及角膜生物测量。结果：术后各术眼角膜屈光力均出现不同程度的降低,ICR厚度与角膜屈光力变化之间存在直线相关（Y=1.4353－32.87X）。术后角膜屈光力稳定。角膜切口愈合良好,中央角膜保持透明。结论：ICR植入术是一种安全、有效、预测性好、屈光效果稳定的角膜屈光手术。

Bhanges of corneal refractive power aftert he implantation of intrastromal corneal ring

Objective To evaluate the safety and efficacy of the refractive effect produced by the implantation of intrastromal comeal ring (ICR). Methods Each of the 60 eyes (30 rabbits) received an ICR. The thickness of the ICRs varied from 0. 19 mm to 0. 41 mm. Each eye underwent a preoperative and postoperative examinations at the lst,3 rd,7 th and 14 th day; the lst,3 rd and 6 th month. Slit-lamp hiomicroscopy and an ORBSCAN'" slit scan comeal tomography/ pachymetry system were performed at predetermined intervals throughout the follow-up periods. Results The decrease of comeal curvature was observed after ICR implantation in all of the eyes. There was a direct relationship between the ICR thickness and the degree of comeal flat tening achieved. The equation is: D = 1. 4353 - 32. 87 x thickness. The postoperative refractive effect was stable. Wound healing was uncomplicated and central cornea remained transparent. Conclusion The ICR implantation is safe and effective and the refractive effect is predictive and stable.