| 乙型肝炎病毒血清标志物与HBV—DNA定量联合检测的意义 |
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| 引用本文： | 蒋丽华,曹进平,冯岚.乙型肝炎病毒血清标志物与HBV—DNA定量联合检测的意义[J].检验医学与临床,2009,6(19):1630-1631. |
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| 作者姓名： | 蒋丽华 曹进平 冯岚 |
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| 作者单位： | 安徽省芜湖市第二人民医院检验科,241000 |
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| 摘 要： | 目的探讨乙型肝炎（下称乙肝）病毒DNA（HBV-DNA）与血清免疫标志物的关系。方法荧光定量聚合酶链反应法（FO-PCR）检测血清样本中HBV—DNA含量；酶联免疫吸附法（ELISA）检测HBV血清标志物。结果A组（大三阳）、B组（小三阳）、C组乙肝表面抗原（HBsAg）、乙肝e抗原（HBeAg）阳性]、D组（HBsAg、抗-HBc阳性）阳性率分别为97．3％、57．8％、100％、54．3％，HBeAg阳性组和HBeAg阴性组HBV-DNA病毒载量差异有统计学意义（P〈0．05）。结论HBV—DNA与乙肝血清标志物乙肝两对半（HBV-M）联合检测，能更准确地反映HBV复制情况，更有助于临床疾病的诊治。
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| 关 键 词： | 乙型肝炎病毒 荧光定量聚合酶链反应法 血清免疫标志物 |
The relationship between HBV DNA and HBV immune Markers in the serum of hepertitis B virus |
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| JIANG Li-hua,CAO Jin-ping,FENG Lan.The relationship between HBV DNA and HBV immune Markers in the serum of hepertitis B virus[J].Laboratory Medicine and Clinic,2009,6(19):1630-1631. |
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| Authors: | JIANG Li-hua CAO Jin-ping FENG Lan |
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| Institution: | .( Department of Clinical Laboratory of the Second People＇s Hospital in Wufu City Anhuei 241000, China) |
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| Abstract: | Objective To explore the relationship between HBV-DNA and HBV immune markers in serum. Methods HBV-DNA in the serum were determined by FQ-PCR and serum HBV maekers were tested by ELISA method. Results The level of each group （A,B,C,D）with HBV DNA（＋） were 97.30%,57.8% ,100% ,54.3% re speetively. Meanwhile,there was significant difference between the two groups of HBeAg （＋） and HBeAg （-） of the level of HBV DNA. Conclusion Detection of HBV-DNA and HBV-M can exactly show the reproduction of HBV, and help to diagnose and treat the disease in clinic. |
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| Keywords: | hepatitis B virus FQ-PCR HBV immune markers |
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