GC法同时测定通络祛痛膏中樟脑、薄荷脑和冰片的含量

目的:建立同步测定通络祛痛膏中樟脑、薄荷脑和冰片等3种成分含量的气相色谱方法。方法:挥发油测定器蒸馏制备供试液,以萘为内标物。HP-INNOWAX毛细管色谱柱,氮气为载气,FID检测器,柱温140℃,内标法测定样品中3种成分的含量。结果:通络祛痛膏中樟脑、薄荷脑和冰片(龙脑和异龙脑)及内标物萘等4种物质在同一色谱条件下获得良好分离,樟脑、薄荷脑和冰片(龙脑和异龙脑)的回收率分别为96.2%(RSD=0.78%),96.8%(RSD=0.76%),96.9%(RSD=1.4%)。采用此法对12批样品进行含量测定,均取得了满意的结果。结论:该方法简便、准确,分离度好,可用于控制通络祛痛膏的质量。

GC simultaneous determination of camphor,menthol and synthetic borneol in Tongluo Qutong plaster

Objective:To establish the determination method of camphor,menthol and synthetic borneol in Tongluo Qutong plaster.Methods:The sample solution was distilled in volatile oil determination apparatus.Naphthalene was used as the internal standard.HP-INNOWAX capillary column was adopted,nitrogen as the carrier gas,and FID as the detector.The column temperature at 140 ℃.Results:Camphor,menthol and synthetic borneol l(borneol and isborneol) in Tangluo Qutong Plaster and naphthalene have been separated well.The average recovery rates of camphor,menthol and synthetic borneol were 96.2%(RSD=0.78%),96.8%(RSD=0.76%) and 96.9%(RSD=1.4%),respectively.Conclusion:The methord is simple,accurate and separable,and can be used to control the quality of Tongluo Qutong plaster.