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肝癌发生的相关分子机制研究进展
引用本文:于秀石,关媛媛,田菊霞. 肝癌发生的相关分子机制研究进展[J]. 杭州医学高等专科学校学报, 2010, 0(5): 390-393
作者姓名:于秀石  关媛媛  田菊霞
作者单位:杭州师范大学基础医学部,浙江杭州310036
摘    要:原发性肝癌是最常见的恶性肿瘤之一,它的发生是外环境致癌因素和自身遗传影响因素协同作用的结果。明确原发性肝癌的发生机制对预防和治疗原发性肝癌具有重要意义。文章对原发性肝癌发生的相关分子机制进行了综述。

关 键 词:肝癌  原癌基因  抑癌基因  信号通路

Progresses in Research of Molecular Mechanisms for Hepatocarcinogenesis
YU Xiu-shi,GUAN Yuan-yuan,TIAN Ju-xia. Progresses in Research of Molecular Mechanisms for Hepatocarcinogenesis[J]. Journal of Hangzhou Medical College, 2010, 0(5): 390-393
Authors:YU Xiu-shi  GUAN Yuan-yuan  TIAN Ju-xia
Affiliation:( Department of Basic Medicine, Hangzhou Normal University, Hangzhou, Zhejiang 310036, China)
Abstract:Primary hepatoeellular carcinoma is one of the most common malignant tumors and the occurrence of liver cancinoma is a synergistic action by external environmental carcinogens and their own genetic factors. It is significant to clarify the molecular mechanisms of hcpatocarcinogenesis for the prevention and treatment of primary hepatocellular carcinoma. This review mainly discusses the molecular mechanisms for hepatoearcinogenesis.
Keywords:Hepatoeellular carcinoma  Proto-oneogene  Tumor suppressor gene  Signaling pathway
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