| 盐酸哌替啶注射液细菌内毒素检查方法研究 |
| |
| 引用本文： | 邓英贤,嵇扬,王文俊,沈娟,聂渝琼,罗晓茹. 盐酸哌替啶注射液细菌内毒素检查方法研究[J]. 解放军药学学报, 2007, 23(4): 315-317 |
| |
| 作者姓名： | 邓英贤 嵇扬 王文俊 沈娟 聂渝琼 罗晓茹 |
| |
| 作者单位： | 空军总医院,药剂科,北京,100036;总后勤部卫生部药品仪器检验所,药理室,北京,100071 |
| |
| 摘 要： | 目的建立盐酸哌替啶注射液细菌内毒素检查法。方法采用《中国药典》2005年版附录细菌内毒素检查法。结果盐酸哌替啶注射液经40倍稀释后,用灵敏度为0.25EU·ml^-1的鲎试剂检测,无干扰因素的影响。结论盐酸哌替啶注射液可应用鲎试剂进行细菌内毒素检查。
|
| 关 键 词： | 盐酸哌替啶注射液 细菌内毒素 干扰试验 |
| 文章编号： | 1008-9926（2007）04-0315-03 |
| 修稿时间： | 2006-07-182006-10-22 |
Application of Bacterial Endotoxin Test to Meperidine Hydrochloride Injection |
| |
| DENG Ying-Xian,JI Yang,WANG Wen-Jun,SGEB Juan,NIE Yu-Qiong,LUO Xiao-Ru. Application of Bacterial Endotoxin Test to Meperidine Hydrochloride Injection[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2007, 23(4): 315-317 |
| |
| Authors: | DENG Ying-Xian JI Yang WANG Wen-Jun SGEB Juan NIE Yu-Qiong LUO Xiao-Ru |
| |
| Affiliation: | 1.Department of Pharmacy,Air Force General Hospital, Beijing 100036 China;2.Drug and Instrument Inspection Institute of General Logistics Department PLA, Beijing 100071 China |
| |
| Abstract: | Aim To apply the bacterial endotoxin test to meperidine hydrochloride injection. Methods According to the bacterial endotoxin test in Chinese pharmacopoeia 2005 edition. Results It was proved that the maximum noninterference concentration was 40 times diluted liquid and the sensitivity of TAL was 0.25EU·ml^-1. Conclusion The results suggested that bacterial endotoxin test is suitable for the detection of endotoxin in meperidine hydrochloride injection. |
| |
| Keywords: | Meperidine hydrochloride injection Bacterial endotoxin test Interfere factors test |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
