| 代谢组学在子痫前期预测及诊断中的应用 |
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| 引用本文： | 孙丽洲,姜子燕. 代谢组学在子痫前期预测及诊断中的应用[J]. 中国实用妇科与产科杂志, 2018, 34(9): 970-973. DOI: DOI：10.19538/j.fk2018090106 |
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| 作者姓名： | 孙丽洲 姜子燕 |
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| 作者单位： | 南京医科大学第一附属医院（江苏省人民医院），江苏 南京 210029 |
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| 基金项目： | 国家自然科学基金面上项目（81771603）；江苏省十三五医学重点学科（产科） |
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| 摘 要： | 通过不同代谢组学技术检测子痫前期患者血清、尿液及胎盘组织中差异代谢产物表达，提出联合多种代谢产物能够显著提高预测及诊断子痫前期的敏感性及特异性，可为子痫前期尤其是早发子痫前期的预测及诊断提供良好的生物学标志物。
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| 关 键 词： | 子痫前期 代谢组学 预测 诊断 |
Application of metabolomics in preeclampsia prediction and diagnosis. |
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| UN Li-zhou,JIANG Zi-yan. Application of metabolomics in preeclampsia prediction and diagnosis.[J]. Chinese Journal of Practical Gynecology and Obstetrics, 2018, 34(9): 970-973. DOI: DOI：10.19538/j.fk2018090106 |
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| Authors: | UN Li-zhou JIANG Zi-yan |
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| Affiliation: | The First Affiliated Hospital of Nanjing Medical University，Nanjing 210029，China |
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| Abstract: | We detected the expression of metabolites in serum，urine and placental tissue by different metabolomic technologies.We put forward that the combination of a variety of metabolites could significantly increase the sensitivity and specificity of prediction and diagnosis of pre-elampsia，especially the early-onset preeclampsia. The study will provide good makers for the prediction and diagnosis of preeclampsia. |
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| Keywords: | preeclampsia metabolomics prediction diagnosis |
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