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基于DTI复杂网络的两性大脑差异性研究
引用本文:俞宙,陶玲,钱志余,武江芬,赵翠花. 基于DTI复杂网络的两性大脑差异性研究[J]. 生物医学工程研究, 2014, 0(3): 147-151
作者姓名:俞宙  陶玲  钱志余  武江芬  赵翠花
作者单位:南京航空航天大学自动化学院,南京,210016
基金项目:国家自然科学基金资助项目(61075107)。
摘    要:为解释男女大脑差异是如何影响人们的思维和行为的,我们利用DTI复杂网络技术对男女两性大脑的差异性进行了定量分析。将44例健康志愿者分成男女两组,利用磁共振弥散张量成像对志愿者进行扫描和数据采集,通过构建脑白质纤维结构网络,并结合图论知识和复杂网络特征度量参数,对男女大脑结构差异及其在功能上的体现进行分析。对两组志愿者的脑结构网络分析发现,男女两组志愿者均具有小世界属性。结构网络局部参数分析显示,男女在涉及语言、情感、运动、方向感等的脑区具有显著差异。男女两性大脑生理结构的差别确实会导致大脑在功能上出现差别,两性大脑在功能上的差别可认为是两性在负责相关功能的脑区所具有的差异所导致。

关 键 词:磁共振弥散张量成像  脑结构网络  小世界属性  网络参数  两性差异

Research of Brain Differences between the Sexes based on DTI Complex Networks
YU Zhou,TAO Ling,QIAN Zhiyu,WU Jiangfen,ZHAO Cuihua. Research of Brain Differences between the Sexes based on DTI Complex Networks[J]. Journal Of Blomedical Englneerlng Research, 2014, 0(3): 147-151
Authors:YU Zhou  TAO Ling  QIAN Zhiyu  WU Jiangfen  ZHAO Cuihua
Affiliation:( College of Automation, Nanjing University of Aeronautics & Astronautics, Nanjing 210016, China)
Abstract:To explain how the brain differences between men and women affect people’s thinking and behavior,we made an quantitative analysis for the brain differences between the sexes based on DTI complex network technology. 44 cases of healthy volunteers were divided into female group and male group. The data were collected by magnetic resonance diffusion tensor imaging scan. The differences of brain structural between the sexes and their corresponding functional manifestation were analyzed by constructing brain structure network based on white matter fiber and using graph theory and the characteristics parameters of complex networks. Both groups showed small- world property. There were significant gender differences in the brain regions involved in language,emotional,motor skills and orientation. The brain structural differences between the sexes does lead to the functional difference. The brain functional differences between sexes can be thought to be caused by the brain regions difference responsible for related functions.
Keywords:Magnetic resonance diffusion tensor imaging ( DTI)  Human brain anatomical networks  Small-world property  Net-work parameters  Sex difference
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