Distinguishing intracerebral hemorrhages caused by arteriovenous malformations |
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Authors: | Ko N U Johnston S C Young W L Singh V Klatsky A L |
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Affiliation: | Department of Neurology, University of California at San Francisco, California 94143-0114, USA. nko@itsa.ucsf.edu |
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Abstract: | BACKGROUND: There is a shortage of data addressing the clinical characteristics of patients with arteriovenous malformations (AVMs) who present with intracerebral hemorrhages (ICH). METHODS: A retrospective cohort study of members of a large, pre-paid health care program was conducted to identify factors that distinguish ICH secondary to cerebral AVMs from all other causes. Univariate and multivariate analysis was performed using Student's t test, Wilcoxon rank-sum test, and logistic regression. RESULTS: Patients with an underlying AVM were younger and more likely to be female, non-smokers with lower blood pressures, lower cholesterol, and lower white blood cell counts on presentation. CONCLUSIONS: These clinical characteristics may be useful in defining potential risk factors in future prospective studies as well as targeting candidates for additional imaging studies after ICH with no apparent etiology. |
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