慢性阻塞性肺疾病急性加重患者的机械通气指南(2007)

慢性阻塞性肺疾病（COPD）是一种常见的慢性呼吸系统疾病，患病人数多，病死率高，严重影响患者的劳动能力和生活质量。2002年世界卫生组织（WHO）公布的资料显示，COPD是目前世界上死亡的第五位病因，预计到2020年，COPD将成为第三位死亡病因。COPD急性加重（AECOPD）合并呼吸衰竭（呼衰）是导致COPD患者住院最重要的原因，加强对AECOPD的防治，特别是提高机械通气技术的应用水平，对提高AECOPD合并呼衰的抢救成功率具有重要意义。

Guideline for mechanical ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease(2007)

OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is one of the major causes of chronic morbidity and mortality throughout the world, while acute exacerbation of COPD (AECOPD) is one of the important causes for the patient to be hospitalized. As COPD is a disease state characterized by irreversible airflow limitation and dynamic pulmonary hyperinflation, the mechanical ventilation strategy for its AECOPD is different from other diseases. To improve the clinical result of mechanical ventilation for AECOPD, Chinese Society of Critical Care Medicine of Chinese Medical Association held a consensus conference to draft a guideline by categorizing all the information gathered from the literature into five grades from A to E, with A being the highest, according to a modified Delphi criteria. The main recommendations were as follows: 1. Noninvasive positive ventilation (NPPV) should be the routine option for AECOPD patients, particularly in hospitalized patients with mild to moderate exacerbations (7.25